Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALPL | P05186 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715587 | 0.83 | KMT2A (0.71) | MEN1KMT2AHTTPKMNPSR1 | |
| SCHEMBL10032040 | 0.81 | KMT2A (0.68) | MEN1KMT2AHTTPKMNPSR1 | |
| SCHEMBL20715319 | 0.80 | MAPK1 (0.68) | MEN1KMT2AHTTPKMNPSR1 | |
| SCHEMBL3024216 | 0.78 | ALDH1A1 (0.73) | MEN1KMT2AHTTPKMNPSR1 | |
| SCHEMBL1170660 | 0.77 | ALDH1A1 (0.86) | MEN1KMT2AHTTPKMNPSR1 | |
| SCHEMBL20715686 | 0.76 | LMNA (0.78) | MEN1KMT2AHTTPKMLMNA | |
| Hydrochloric Acid SCHEMBL8607035 | 0.75 | PKM (0.67) | MEN1KMT2AHTTPKMLMNA | |
| SCHEMBL28972318 | 0.75 | ALDH1A1 (0.61) | MEN1KMT2AHTTNPSR1LMNA | |
| SCHEMBL30063611 | 0.75 | ALDH1A1 (0.61) | MEN1KMT2AHTTNPSR1LMNA | |
| SCHEMBL30021380 | 0.74 | MEN1 (0.68) | MEN1KMT2AHTTPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142682-A1 | ANTIVIRULENCE COMPOUNDS INHIBITING BACTERIAL MONO-ADP-RIBOSYLTRANSFERASE TOXINS | UNIVERSITY OF GUELPH (CA) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142682-A1 | ANTIVIRULENCE COMPOUNDS INHIBITING BACTERIAL MONO-ADP-RIBOSYLTRANSFERASE TOXINS | TIPARP, CD38, PARP14 | MEN1 2490/4885KMT2A 1500/4885HTT 1338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.