Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 6/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15564992 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL28329648 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL28199238 | 0.80 | CYP2A6 (0.42) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL16406012 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL22190239 | 0.76 | APP (0.59) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL22190246 | 0.76 | APP (0.59) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL4860318 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL25191403 | 0.75 | APP (0.43) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL4173773 | 0.75 | TSHR (0.47) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL5429778 | 0.75 | CYP2A6 (0.50) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487080-B2 | Fluorine-labeled compounds | GENERAL ELECTRIC COMPANY (US) | 2013-07-16 | — | — | US | disclosed |
| US-8124725-B2 | PDGF-Rβ binders | GENERAL ELECTRIC COMPANY (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110160430-A1 | FLUORINE-LABELED COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2011-06-30 | — | — | US | disclosed |
| US-7902332-B2 | Reacting thiol-reactive terminus of linker with a polypeptide and fluorine-substituted aldehyde | GENERAL ELECTRIC COMPANY (US) | 2011-03-08 | — | — | US | disclosed |
| US-20090191124-A1 | PDGF-RBeta BINDERS | GENERAL ELECTRIC COMPANY (US) | 2009-07-30 | — | — | US | disclosed |
| US-20080139787-A1 | Fluorine-labeled compounds | GENERAL ELECTRIC COMPANY | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139787-A1 | Fluorine-labeled compounds | PFAS, DHFR, PAICS | ALDH1A1 226/4885MAPT 2125/4885LMNA 3929/4885 |
| US-20110160430-A1 | FLUORINE-LABELED COMPOUNDS | PFAS, DHFR, PAICS | ALDH1A1 226/4885MAPT 2125/4885LMNA 3929/4885 |
| US-20090191124-A1 | PDGF-RBeta BINDERS | PDGFRB, PDGFA, PDGFRA | ALDH1A1 2996/4885MAPT 3399/4885LMNA 3074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.