SCHEMBL10032333

SCHEMBL10032333

Cc1ccc2ccc3ccc(-c4ccc(-c5ccc6ccc7ccc(C)nc7c6n5)c5ccccc45)nc3c2n1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.58
RAB9A P51151 1/20 0.58
CCR5 P51681 1/20 0.58
METAP2 P50579 1/20 0.44
AR P10275 5/20 0.44
SLC40A1 Q9NP59 2/20 0.42
CYP1A2 P05177 1/20 0.41
MAPT P10636 2/20 0.40
GAA P10253 1/20 0.40
CRHR1 P34998 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PARP1 P09874 1/20 0.39
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
GLO1 Q04760 2/20 0.37
AGTR1 P30556 1/20 0.36
PAX8 Q06710 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032334 0.92 CCR1 (0.58) CCR1RAB9ACCR5METAP2AR
SCHEMBL10032294 0.83 AR (0.54) RAB9AMETAP2ARCYP1A2MAPT
SCHEMBL10032369 0.81 AR (0.49) CCR1CCR5ARCYP1A2MAPT
SCHEMBL10032277 0.80 KDM4E (0.41) RAB9AARCYP1A2MAPTL3MBTL1
SCHEMBL10032335 0.79 AR (0.40) CCR1CCR5ARCYP1A2CRHR1
SCHEMBL10032262 0.79 CYP1A2 (0.43) CCR1RAB9ACCR5ARCYP1A2
SCHEMBL9611715 0.78 RAB9A (0.60) CCR1RAB9ACCR5METAP2CYP1A2
SCHEMBL10032295 0.78 ALDH1A1 (0.49) ARMAPTL3MBTL1KDM4EALDH1A1
SCHEMBL12112695 0.78 CCR1 (0.60) CCR1RAB9ACCR5METAP2AR
SCHEMBL10032332 0.78 PARP1 (0.47) RAB9AARMAPTL3MBTL1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573823-B2 Organic electroluminescent device JOLED INC (JP) 2020-02-25 US disclosed
EP-2833429-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT JOLED INC (JP) 2019-09-18 EP disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-9923153-B2 Organic light emitting diode comprising an organic semiconductor layer NOVALED GMBH (DE) 2018-03-20 US disclosed
US-9923153-B2 Organic light emitting diode comprising an organic semiconductor layer NOVALED GMBH (DE) 2018-03-20 US disclosed
US-20170346037-A1 Organic Light Emitting Diode Comprising an Organic Semiconductor Layer NOVALED GMBH (DE) 2017-11-30 US disclosed
US-20170346023-A1 Organic Light Emitting Diode Comprising an Organic Semiconductor Layer NOVALED GMBH (DE) 2017-11-30 US disclosed
US-20170346023-A1 Organic Light Emitting Diode Comprising an Organic Semiconductor Layer NOVALED GMBH (DE) 2017-11-30 US disclosed
US-20170346037-A1 Organic Light Emitting Diode Comprising an Organic Semiconductor Layer NOVALED GMBH (DE) 2017-11-30 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed
US-20070267958-A1 Material for Light Emitting Device and Light Emitting Device TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed
US-20070267958-A1 Material for Light Emitting Device and Light Emitting Device TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573823-B2 Organic electroluminescent device L1CAM, NES, EML4 CCR1 2156/4885RAB9A 2116/4885CCR5 2741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.