SCHEMBL10032335

SCHEMBL10032335

Cc1cc(C)cc(-c2ccc3ccc4ccc(-c5ccc(-c6ccc7ccc8ccc(-c9cc(C)cc(C)c9)nc8c7n6)c6ccccc56)nc4c3n2)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AR P10275 8/20 0.40
BRD9 Q9H8M2 1/20 0.37
BRD7 Q9NPI1 1/20 0.37
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.33
CCR1 P32246 1/20 0.33
CCR5 P51681 1/20 0.33
CCR8 P51685 1/20 0.33
CRHR1 P34998 1/20 0.33
PSMB5 P28074 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032277 0.85 KDM4E (0.41) ARADORA2ACYP1A2KDM4EALDH1A1
SCHEMBL25776067 0.85 MAOA (0.43) ARADORA2AADORA1CYP1A2CYP2A6
SCHEMBL10032446 0.84 AR (0.37) ARBRD9BRD7CYP1A2CYP2A6
SCHEMBL10032399 0.84 CCR1 (0.41) ADORA2AADORA1CYP1A2CYP2A6CCR1
SCHEMBL10032292 0.82 RAB9A (0.39) ADORA2AADORA1KDM4EALDH1A1HPGD
SCHEMBL10032284 0.81 PARP1 (0.45) ADORA2AADORA1CYP1A2KDM4EALDH1A1
SCHEMBL10032328 0.81 KMO (0.40) ADORA2AADORA1KDM4E
SCHEMBL10032332 0.80 PARP1 (0.47) ARADORA2AADORA1KDM4EALDH1A1
SCHEMBL30112629 0.80 CCR1 (0.56) CYP1A2KDM4EALDH1A1HPGDKMT2A
SCHEMBL10032262 0.80 CYP1A2 (0.43) ARCYP1A2CYP2A6KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed
US-20070267958-A1 Material for Light Emitting Device and Light Emitting Device TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed
US-20070267958-A1 Material for Light Emitting Device and Light Emitting Device TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed