SCHEMBL10032399

SCHEMBL10032399

Cc1cc(C)cc(-c2ccc3ccc4ccc(-c5cc(-c6ccc7ccc8ccc(-c9cc(C)cc(C)c9)nc8c7n6)cc(-c6ccc7ccc8ccc(-c9cc(C)cc(C)c9)nc8c7n6)c5)nc4c3n2)c1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.41
CCR5 P51681 3/20 0.41
RAB9A P51151 2/20 0.41
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
CCR8 P51685 2/20 0.35
CYP1A2 P05177 2/20 0.33
CYP2A6 P11509 2/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
MAP4K4 O95819 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032292 0.94 RAB9A (0.39) CCR1CCR5RAB9AADORA2AADORA1
SCHEMBL10032328 0.92 KMO (0.40) RAB9AADORA2AADORA1NPC1MAP4K4
SCHEMBL10032284 0.88 PARP1 (0.45) RAB9AADORA2AADORA1CYP1A2NPC1
SCHEMBL10032480 0.85 SMN1; SMN2 (0.44) CCR1CCR5RAB9ANPC1
SCHEMBL30112629 0.84 CCR1 (0.56) CCR1CCR5CCR8CYP1A2
SCHEMBL10032335 0.84 AR (0.40) CCR1CCR5ADORA2AADORA1CCR8
SCHEMBL10032538 0.83 CCR1 (0.65) CCR1CCR5RAB9ACYP1A2CYP2A6
SCHEMBL11962231 0.82 CNR2 (0.35) CCR1CCR5RAB9ANPC1
SCHEMBL25776067 0.81 MAOA (0.43) ADORA2AADORA1CYP1A2CYP2A6
SCHEMBL14420889 0.80 NOTUM (0.42) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed
US-20070267958-A1 Material for Light Emitting Device and Light Emitting Device TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed
US-20070267958-A1 Material for Light Emitting Device and Light Emitting Device TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed