SCHEMBL10032480

SCHEMBL10032480

Cc1ccc(-c2ccc3ccc4ccc(-c5cc(-c6ccc7ccc8ccc(-c9ccc(C)cc9)nc8c7n6)cc(-c6ccc7ccc8ccc(-c9ccc(C)cc9)nc8c7n6)c5)nc4c3n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.44
KMT2A Q03164 7/20 0.43
MEN1 O00255 6/20 0.43
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 4/20 0.43
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
HPGD P15428 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ENPP3 O14638 1/20 0.41
ENPP1 P22413 1/20 0.41
GAK O14976 1/20 0.40
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40
LMNA P02545 2/20 0.40
MITF O75030 1/20 0.40
KDM5A P29375 1/20 0.40
KDM5C P41229 1/20 0.40
PAX8 Q06710 1/20 0.40
TP53 P04637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032244 0.94 SMN1; SMN2 (0.48) SMN1; SMN2KMT2AMEN1KDM4EALDH1A1
SCHEMBL8477633 0.94 SMN1; SMN2 (0.48) SMN1; SMN2KMT2AMEN1KDM4EALDH1A1
SCHEMBL10032338 0.91 ENPP3 (0.48) SMN1; SMN2KMT2AMEN1KDM4EALDH1A1
SCHEMBL10032365 0.90 MEN1 (0.47) SMN1; SMN2KMT2AMEN1KDM4EALDH1A1
SCHEMBL10032440 0.89 MEN1 (0.46) SMN1; SMN2KMT2AMEN1KDM4EALDH1A1
SCHEMBL10032270 0.88 CTRC (0.46) SMN1; SMN2KMT2AMEN1KDM4EALDH1A1
SCHEMBL10032292 0.88 RAB9A (0.39) SMN1; SMN2KMT2AMEN1KDM4EALDH1A1
SCHEMBL10032399 0.85 CCR1 (0.41) RAB9ANPC1CCR1CCR5
SCHEMBL10032284 0.82 PARP1 (0.45) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL11962281 0.82 TEAD4 (0.44) SMN1; SMN2KMT2AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed
US-8114529-B2 Material for lighting emitting device and light emitting device TORAY INDUSTRIES, INC. (JP) 2012-02-14 US disclosed
US-20070267958-A1 Material for Light Emitting Device and Light Emitting Device TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed
US-20070267958-A1 Material for Light Emitting Device and Light Emitting Device TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed