SCHEMBL20176785

SCHEMBL20176785

Cc1ccc(-c2c3ccccc3c(-c3ccc(-c4ccc5ccccc5c4)cc3)c3ccccc23)nc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.42
CYP3A4 P08684 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CCR1 P32246 1/20 0.42
CCR5 P51681 1/20 0.42
CCR8 P51685 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
CTRC Q99895 1/20 0.41
CYP2A6 P11509 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
CYP11B1 P15538 2/20 0.40
CYP11B2 P19099 2/20 0.40
CYP17A1 P05093 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032784 0.92 CCR1 (0.43) CYP1A2CYP3A4ALDH1A1CYP2C9HPGD
SCHEMBL10032752 0.91 CYP3A4 (0.40) CYP1A2CYP3A4ALDH1A1CYP2C9HPGD
SCHEMBL18174590 0.91 CTRC (0.41) CYP1A2CYP3A4ALDH1A1CYP2C9HPGD
SCHEMBL15977779 0.89 CTRC (0.40) CYP1A2CYP3A4ALDH1A1CYP2C9HPGD
SCHEMBL10032679 0.89 CYP3A4 (0.43) CYP3A4ALDH1A1HPGDCCR1CCR5
SCHEMBL10032924 0.88 CYP3A4 (0.42) CYP3A4ALDH1A1HPGDCCR1CCR5
SCHEMBL10032507 0.88 CYP3A4 (0.42) CYP1A2CYP3A4ALDH1A1CYP2C9HPGD
SCHEMBL10032185 0.87 CYP11B2 (0.42) CYP1A2CYP3A4ALDH1A1CYP2C9HPGD
SCHEMBL10032654 0.86 CCR1 (0.43) CYP3A4ALDH1A1HPGDCCR1CCR5
SCHEMBL15977410 0.86 CTRC (0.42) CYP1A2CYP3A4ALDH1A1CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 WO disclosed