Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033134 | 0.90 | USP30 (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1709454 | 0.89 | SLC6A2 (0.40) | KCNN4SLC6A2SLC6A4TAS1R3TAS1R1 | |
| SCHEMBL10033001 | 0.83 | NPC1 (0.38) | ALDH1A1 | |
| SCHEMBL10033003 | 0.81 | EPHX2 (0.45) | EPHX2ALDH1A1 | |
| SCHEMBL1709399 | 0.80 | PTGDR (0.41) | CTSDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1709398 | 0.78 | KDM1A (0.36) | CTSDEPHX1HDAC1HDAC8HDAC6 | |
| SCHEMBL1709359 | 0.78 | USP30 (0.38) | SLC6A2SLC6A4PKMHDAC3HDAC1 | |
| SCHEMBL1709374 | 0.75 | KMT2A (0.39) | ALDH1A1 | |
| SCHEMBL1709358 | 0.75 | DPEP1 (0.36) | SLC6A2SLC6A4TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10032829 | 0.75 | FFAR1 (0.41) | KCNN4TAS1R3TAS1R1TAS1R2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |