Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033188 | 0.87 | MTOR (0.36) | RECQLALDH1A1NPC1HPGDTSHR | |
| SCHEMBL10033178 | 0.85 | L3MBTL1 (0.39) | RECQLALDH1A1NPC1HPGDTSHR | |
| SCHEMBL10032824 | 0.84 | GRIA4 (0.40) | RECQLLMNA | |
| SCHEMBL10033189 | 0.82 | TACR1 (0.39) | RECQLALDH1A1TSHRKDM4E | |
| SCHEMBL10033190 | 0.81 | L3MBTL1 (0.33) | HPGDL3MBTL1LMNATDP1 | |
| SCHEMBL10033185 | 0.78 | RECQL (0.33) | RECQLALDH1A1NPC1HPGDTSHR | |
| SCHEMBL10033112 | 0.78 | BRD4 (0.42) | BRD4ALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL10032830 | 0.77 | GRIA4 (0.41) | RECQLL3MBTL1GAAKDM4E | |
| SCHEMBL10033180 | 0.76 | SLC6A2 (0.34) | HPGDL3MBTL1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL10033184 | 0.75 | L3MBTL1 (0.35) | ALDH1A1HPGDSMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |