Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033089 | 0.84 | HTR2A (0.40) | HTR2AHTR2CHTR2BKDM1AALDH1A1 | |
| SCHEMBL10033086 | 0.83 | KDM1A (0.40) | HTR2CHTR2BKDM1AALDH1A1TDP1 | |
| SCHEMBL1709495 | 0.79 | MEN1 (0.38) | HTR2AHTR2CHTR2BDPP4 | |
| SCHEMBL1709418 | 0.78 | BCHE (0.32) | HTR2AHTR2CHTR2BBCHEACHE | |
| SCHEMBL1709456 | 0.73 | ALDH1A1 (0.45) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL10033088 | 0.73 | KDM1A (0.34) | KDM1A | |
| SCHEMBL6998583 | 0.70 | HTR2C (0.61) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL3422301 | 0.70 | HTR2C (0.61) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL3419759 | 0.70 | HTR2C (0.61) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL3031647 | 0.70 | HTR2C (0.61) | HTR2AHTR2CHTR2BKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |