Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032839 | 0.78 | KDM1A (0.40) | MAOAKDM1ATP53MDM2 | |
| SCHEMBL1709367 | 0.77 | MEN1 (0.46) | SMN1; SMN2TP53MDM2KMT2A | |
| SCHEMBL15805066 | 0.76 | SLC18A2 (0.50) | ALDH1A1HTR2AHTR2CHTR2BKCNN4 | |
| SCHEMBL15805101 | 0.76 | SLC18A2 (0.50) | ALDH1A1HTR2AHTR2CHTR2BKCNN4 | |
| SCHEMBL1011144 | 0.76 | SLC18A2 (0.50) | ALDH1A1HTR2AHTR2CHTR2BKCNN4 | |
| SCHEMBL15797739 | 0.76 | SLC18A2 (0.50) | ALDH1A1HTR2AHTR2CHTR2BKCNN4 | |
| SCHEMBL6918804 | 0.76 | KDM4E (0.45) | ALDH1A1HTR2CMAOAMAOBKDM1A | |
| SCHEMBL1709472 | 0.75 | DGAT1 (0.39) | ALDH1A1MAOAMAOBKDM1ARCOR1 | |
| SCHEMBL1709360 | 0.75 | L3MBTL1 (0.43) | ALDH1A1SMN1; SMN2TP53MDM2KMT2A | |
| SCHEMBL10033085 | 0.73 | HTR2A (0.40) | ALDH1A1HTR2AHTR2CHTR2BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |