Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 5/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033097 | 0.84 | KDM4E (0.39) | HDAC8HDAC6HDAC1 | |
| SCHEMBL10033109 | 0.84 | KDM1A (0.41) | HDAC8HDAC6HDAC1KDM1A | |
| SCHEMBL10033125 | 0.79 | GRIA4 (0.38) | HDAC8HDAC6HDAC1KDM1AGRIA4 | |
| SCHEMBL1709398 | 0.79 | KDM1A (0.36) | HDAC8HDAC6HDAC1KDM1APAX8 | |
| SCHEMBL25222944 | 0.76 | KDM1A (0.42) | KDM1AGRIA4HTT | |
| SCHEMBL10033104 | 0.72 | MEN1 (0.38) | HTTNPC1RAB9A | |
| SCHEMBL10033130 | 0.70 | TACR1 (0.41) | KDM1A | |
| SCHEMBL9166296 | 0.69 | POLB (0.40) | — | |
| SCHEMBL10033102 | 0.69 | PTGDR (0.40) | — | |
| Hydrochloric Acid SCHEMBL28795083 | 0.68 | EPHX2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |