Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033109 | 0.87 | KDM1A (0.41) | HDAC8HDAC6HDAC1ALDH1A1POLB | |
| SCHEMBL10033125 | 0.84 | GRIA4 (0.38) | NPSR1HDAC8HDAC6HDAC1 | |
| SCHEMBL10033099 | 0.84 | CTSC (0.40) | HDAC8HDAC6HDAC1 | |
| SCHEMBL3554788 | 0.81 | HDAC8 (0.50) | HDAC8HDAC6HDAC1 | |
| SCHEMBL10033102 | 0.81 | PTGDR (0.40) | ALDH1A1POLBPTGDRPTGDR2MDM2 | |
| SCHEMBL10033001 | 0.77 | NPC1 (0.38) | ALDH1A1POLBPTGDRPTGDR2MDM2 | |
| SCHEMBL10033104 | 0.75 | MEN1 (0.38) | KDM4ENPSR1ALDH1A1POLBHSD17B10 | |
| SCHEMBL10033095 | 0.75 | L3MBTL1 (0.41) | HPGDNPSR1ALDH1A1 | |
| SCHEMBL10033131 | 0.74 | ALDH1A1 (0.42) | KDM4EHPGDNPSR1ALDH1A1POLB | |
| SCHEMBL10033101 | 0.74 | ALDH1A1 (0.40) | KDM4EALDH1A1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |