Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033097 | 0.81 | KDM4E (0.39) | PTGDRPTGDR2ALDH1A1MDM2POLB | |
| SCHEMBL10033125 | 0.81 | GRIA4 (0.38) | HTR2AHTR2CHTR2B | |
| SCHEMBL1709399 | 0.80 | PTGDR (0.41) | PTGDRPTGDR2OPRL1ALDH1A1L3MBTL1 | |
| SCHEMBL10033128 | 0.78 | ALOX5AP (0.36) | ALDH1A1L3MBTL1KMT2ADPP4CYP11B1 | |
| SCHEMBL10033098 | 0.74 | ALOX5AP (0.39) | ALDH1A1L3MBTL1DPP4CYP11B1CYP11B2 | |
| SCHEMBL10033129 | 0.74 | PPOX (0.36) | ALDH1A1L3MBTL1KMT2ADPP4CYP11B1 | |
| SCHEMBL10033100 | 0.74 | CYP11B1 (0.35) | ALDH1A1L3MBTL1DPP4CYP11B1CYP11B2 | |
| SCHEMBL10033112 | 0.73 | BRD4 (0.42) | ALDH1A1KMT2APOLB | |
| SCHEMBL10033095 | 0.72 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KMT2ADPP4MEN1 | |
| SCHEMBL10033109 | 0.72 | KDM1A (0.41) | ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |