Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009276 | 0.81 | CYP11B2 (0.45) | CYP11B2 | |
| SCHEMBL10033030 | 0.78 | PDE10A (0.35) | DHFRRAB9ASMN1; SMN2 | |
| SCHEMBL2605772 | 0.72 | CYP17A1 (0.36) | CYP11B2 | |
| SCHEMBL10033146 | 0.71 | SMN1; SMN2 (0.35) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25596550 | 0.70 | ALDH1A1 (0.34) | CYP11B2DHFRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25596755 | 0.69 | PLA2G7 (0.39) | CYP11B2 | |
| SCHEMBL10033200 | 0.68 | L3MBTL1 (0.34) | CYP11B2SMN1; SMN2 | |
| SCHEMBL25596754 | 0.68 | CYP11B2 (0.40) | CYP11B2 | |
| SCHEMBL14290733 | 0.68 | ATM (0.33) | — | |
| SCHEMBL10034492 | 0.66 | CYP11B1 (0.38) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012008527-A1 | PYRIMIDINE COMPOUND AND PEST-CONTROL USAGE THEREFOR | 住友化学株式会社 (JP) | 2012-01-19 | — | — | WO | disclosed |