SCHEMBL4656148

SCHEMBL4656148

COc1ccc(C(O)(c2ccc(O)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.61
LTA4H P09960 1/20 0.61
APP P05067 2/20 0.55
CALM1 P0DP23 1/20 0.52
GAA P10253 1/20 0.52
PKM P14618 1/20 0.52
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
AHR P35869 1/20 0.46
S100B P04271 1/20 0.46
MAPT P10636 1/20 0.46
ABL1 P00519 1/20 0.45
ABCB1 P08183 1/20 0.45
BCR P11274 1/20 0.45
NPC1 O15118 1/20 0.45
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3855634 0.92 ESR2 (0.53) ESR2LTA4HAPPCALM1GAA
SCHEMBL812742 0.91 CA1 (0.58) ESR2LTA4HCA12CA1CA2
SCHEMBL21880552 0.84 ESR2 (0.58) ESR2APPCA12CA1CA2
SCHEMBL10033153 0.84 ESR2 (0.64) ESR2LTA4HAPPCALM1GAA
1,4-Dimethoxybenzene SCHEMBL8351066 0.83 ESR2 (0.84) ESR2LTA4HAPPCALM1GAA
Mequinol SCHEMBL166535 0.83 ESR2 (0.84) ESR2LTA4HAPPCALM1GAA
Mequinol SCHEMBL1535640 0.83 ESR2 (0.84) ESR2LTA4HAPPCALM1GAA
Mequinol SCHEMBL21009 0.83
SCHEMBL29205 0.83 CA4 (0.54) LTA4HCA12CA1CA2CA7
SCHEMBL822911 0.83 ESR2 (0.70) ESR2LTA4HAPPCALM1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 EP disclosed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US disclosed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 ESR2 2975/4885LTA4H 1862/4885APP 2229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.