Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033189 | 0.83 | TACR1 (0.39) | RECQLALDH1A1TSHRKDM4E | |
| SCHEMBL10033178 | 0.81 | L3MBTL1 (0.39) | RECQLALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL10032824 | 0.80 | GRIA4 (0.40) | RECQLLMNA | |
| SCHEMBL10033182 | 0.78 | BRD4 (0.38) | RECQLALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL10033188 | 0.76 | MTOR (0.36) | RECQLALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL10033175 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL10032830 | 0.73 | GRIA4 (0.41) | RECQLGAAL3MBTL1KDM4E | |
| SCHEMBL10033116 | 0.72 | L3MBTL1 (0.38) | ALDH1A1HPGDSMN1; SMN2KCNK3GAA | |
| SCHEMBL10033180 | 0.72 | SLC6A2 (0.34) | HPGDKCNK3L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL10033184 | 0.71 | L3MBTL1 (0.35) | ALDH1A1HPGDSMN1; SMN2LMNAKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |