Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.64 |
| ▸ | ITGAV | P06756 | 3/20 | 0.64 |
| ▸ | MC4R | P32245 | 9/20 | 0.52 |
| ▸ | MC5R | P33032 | 9/20 | 0.52 |
| ▸ | MC3R | P41968 | 9/20 | 0.52 |
| ▸ | MC1R | Q01726 | 9/20 | 0.52 |
| ▸ | CTSG | P08311 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | GRB7 | Q14451 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15247340 | 0.85 | ITGB3 (0.52) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL14096946 | 0.85 | MC4R (0.59) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL14970192 | 0.84 | MC4R (0.56) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL14004123 | 0.84 | TSLP (0.57) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL9908255 | 0.84 | MC4R (0.57) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL11928873 | 0.83 | MC4R (0.56) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL12407321 | 0.83 | CTSG (0.53) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL15623628 | 0.83 | MC4R (0.57) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL12482122 | 0.83 | MC4R (0.57) | ITGB3ITGAVMC4RMC5RMC3R | |
| SCHEMBL12918029 | 0.83 | MC4R (0.57) | ITGB3ITGAVMC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022227-A1 | RADIOLABELLING REAGENTS AND METHODS | GE HEALTHCARE LIMITED (GB) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022227-A1 | RADIOLABELLING REAGENTS AND METHODS | ANPEP, DNPEP, QRFPR | ITGB3 1205/4885ITGAV 1529/4885MC4R 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.