Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033647 | 0.89 | NPSR1 (0.43) | RORCNR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL10033645 | 0.84 | ALDH1A1 (0.50) | POLBMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10033639 | 0.82 | NAPRT (0.58) | POLBMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10033649 | 0.80 | ALDH1A1 (0.46) | POLBMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL14997857 | 0.80 | MAPT (0.58) | POLBMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10033644 | 0.79 | ALDH1A1 (0.41) | POLBMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL10033642 | 0.78 | TRPV1 (0.41) | POLBALDH1A1NPSR1GAAHTT | |
| SCHEMBL10033640 | 0.78 | MEN1 (0.57) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10033643 | 0.77 | RXFP1 (0.48) | KMT2AALDH1A1NPSR1TP53LMNA | |
| SCHEMBL5151866 | 0.76 | KMT2A (0.74) | RORCNR1H4POLBFFAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742156-B2 | Anti-viral carbamimidothioic acid esters | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2014-06-03 | — | — | US | disclosed |
| US-8742156-B2 | Anti-viral carbamimidothioic acid esters | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2014-06-03 | — | — | US | disclosed |
| US-20130143961-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | BRITISH COLUMBIA CANCER AGENCY (CA) | 2013-06-06 | — | — | US | disclosed |
| US-20130143961-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | BRITISH COLUMBIA CANCER AGENCY (CA) | 2013-06-06 | — | — | US | disclosed |
| WO-2012021991-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | VERSITECH LIMITED (CN) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143961-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | NAT10, RNGTT, NSUN2 | RORC 1946/4885NR1H4 2036/4885POLB 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.