Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997857 | 0.86 | MAPT (0.58) | ALDH1A1NPSR1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10033645 | 0.84 | ALDH1A1 (0.50) | ALDH1A1NPSR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10033647 | 0.83 | NPSR1 (0.43) | ALDH1A1NPSR1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL10033640 | 0.83 | MEN1 (0.57) | ALDH1A1KMT2ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL10033639 | 0.82 | NAPRT (0.58) | ALDH1A1NPSR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10033643 | 0.82 | RXFP1 (0.48) | ALDH1A1NPSR1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10033646 | 0.80 | RORC (0.50) | ALDH1A1NPSR1KMT2AMEN1POLB | |
| SCHEMBL10033641 | 0.79 | CA1 (0.57) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL14997856 | 0.76 | PTGS2 (0.48) | ALDH1A1NPSR1 | |
| SCHEMBL10033637 | 0.75 | MAPT (0.47) | ALDH1A1NPSR1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742156-B2 | Anti-viral carbamimidothioic acid esters | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2014-06-03 | — | — | US | disclosed |
| US-8742156-B2 | Anti-viral carbamimidothioic acid esters | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2014-06-03 | — | — | US | disclosed |
| US-20130143961-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | BRITISH COLUMBIA CANCER AGENCY (CA) | 2013-06-06 | — | — | US | disclosed |
| US-20130143961-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | BRITISH COLUMBIA CANCER AGENCY (CA) | 2013-06-06 | — | — | US | disclosed |
| WO-2012021991-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | VERSITECH LIMITED (CN) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143961-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | NAT10, RNGTT, NSUN2 | ALDH1A1 1165/4885NPSR1 2283/4885KMT2A 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.