Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033644 | 0.88 | ALDH1A1 (0.41) | ALDH1A1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10033636 | 0.84 | LMNA (0.46) | PPARAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10033645 | 0.82 | ALDH1A1 (0.50) | ALDH1A1NPSR1NOS1NPC1RAB9A | |
| SCHEMBL10033640 | 0.78 | MEN1 (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL10033646 | 0.78 | RORC (0.50) | ALDH1A1NPSR1POLBGAAHTT | |
| SCHEMBL10033639 | 0.77 | NAPRT (0.58) | ALDH1A1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10033637 | 0.76 | MAPT (0.47) | ALDH1A1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10033647 | 0.76 | NPSR1 (0.43) | ALDH1A1NPSR1NOS1NPC1RAB9A | |
| SCHEMBL14997857 | 0.75 | MAPT (0.58) | ALDH1A1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14997856 | 0.74 | PTGS2 (0.48) | ALDH1A1NPSR1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742156-B2 | Anti-viral carbamimidothioic acid esters | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2014-06-03 | — | — | US | disclosed |
| US-8742156-B2 | Anti-viral carbamimidothioic acid esters | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2014-06-03 | — | — | US | disclosed |
| US-20130143961-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | BRITISH COLUMBIA CANCER AGENCY (CA) | 2013-06-06 | — | — | US | disclosed |
| US-20130143961-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | BRITISH COLUMBIA CANCER AGENCY (CA) | 2013-06-06 | — | — | US | disclosed |
| WO-2012021991-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | VERSITECH LIMITED (CN) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143961-A1 | ANTI-VIRAL CARBAMIMIDOTHIOIC ACID ESTERS | NAT10, RNGTT, NSUN2 | TRPV1 4265/4885PPARA 235/4885ALDH1A1 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.