Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033921 | 0.90 | ALDH1A1 (0.44) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10033924 | 0.89 | GPX4 (0.40) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10033894 | 0.88 | KMT2A (0.39) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10033926 | 0.87 | KMT2A (0.37) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10033922 | 0.87 | GAA (0.41) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL522589 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL14976523 | 0.71 | MAPT (0.34) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL14986110 | 0.70 | MEN1 (0.35) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL16232504 | 0.67 | MEN1 (0.33) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14976615 | 0.66 | KMT2A (0.33) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029197-A1 | Method for Preparing Sulfur-Containing Compounds | THE ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2012-02-02 | — | — | US | disclosed |
| US-20120029197-A1 | Method for Preparing Sulfur-Containing Compounds | THE ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029197-A1 | Method for Preparing Sulfur-Containing Compounds | SULT1E1, SULT1A1, TST | ALDH1A1 195/4885HTT 3916/4885MAPT 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.