Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.67 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761876 | 0.90 | CYP19A1 (0.80) | SIGMAR1CYP19A1HTR1AACHEMAOB | |
| SCHEMBL30275056 | 0.90 | CYP19A1 (0.80) | SIGMAR1CYP19A1HTR1AACHEMAOB | |
| SCHEMBL28733987 | 0.90 | CYP19A1 (0.80) | SIGMAR1CYP19A1HTR1AACHEMAOB | |
| SCHEMBL10689307 | 0.83 | CYP26A1 (0.52) | SIGMAR1CYP19A1HTR1AACHEMAOB | |
| SCHEMBL15700140 | 0.82 | ACHE (0.56) | SIGMAR1CYP19A1HTR1AACHEHTR7 | |
| SCHEMBL3033688 | 0.81 | CYP19A1 (0.77) | SIGMAR1CYP19A1HTR1AACHEMAOB | |
| SCHEMBL467521 | 0.81 | ACHE (0.55) | SIGMAR1CYP19A1HTR1AACHEHTR7 | |
| SCHEMBL31112302 | 0.80 | CYP19A1 (0.70) | SIGMAR1CYP19A1HTR1ACYP26A1 | |
| SCHEMBL7247938 | 0.80 | CYP19A1 (0.70) | SIGMAR1CYP19A1HTR1AACHECYP26A1 | |
| SCHEMBL31112261 | 0.80 | CYP19A1 (0.70) | SIGMAR1CYP19A1HTR1AMAOBCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701684-B2 | Chiral fluorinating reagents | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2015-10-08 | — | — | US | disclosed |
| WO-2014068341-A2 | CHIRAL FLUORINATING REAGENTS | ISIS INNOVATION LIMITED (GB) | 2014-05-08 | — | — | WO | disclosed |
| US-20120029197-A1 | Method for Preparing Sulfur-Containing Compounds | THE ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029197-A1 | Method for Preparing Sulfur-Containing Compounds | SULT1E1, SULT1A1, TST | SIGMAR1 273/4885CYP19A1 2086/4885HTR1A 1224/4885 |
| US-20150284401-A1 | CHIRAL FLUORINATING REAGENTS | TIAM1, AFF2, AFF1 | SIGMAR1 158/4885CYP19A1 551/4885HTR1A 2139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.