Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IAPP | P10997 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001729 | 0.93 | HSD17B3 (0.53) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5681582 | 0.86 | HSD17B3 (0.62) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL6812061 | 0.83 | HSD17B3 (0.58) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2427006 | 0.81 | HSD17B3 (0.56) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2239062 | 0.81 | HSP90AA1 (0.58) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL15394620 | 0.80 | PKM (0.64) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5326647 | 0.80 | HSD17B3 (0.55) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL30266750 | 0.79 | SLC22A6 (0.64) | HSD17B3RAB9AMEN1KMT2A | |
| SCHEMBL3811067 | 0.79 | SLC22A6 (0.64) | HSD17B3RAB9AMEN1KMT2A | |
| SCHEMBL26254861 | 0.79 | HSD17B3 (0.82) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8652444-B2 | Oral compositions containing biphenol antibacterial compounds | COLGATE-PALMOLIVE COMPANY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20120052026-A1 | ORAL COMPOSITIONS CONTAINING BIPHENOL ANTIBACTERIAL COMPOUNDS | COLGATE-PALMOLIVE COMPANY (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052026-A1 | ORAL COMPOSITIONS CONTAINING BIPHENOL ANTIBACTERIAL COMPOUNDS | BPGM, ABCB11, UGT1A10 | HSD17B3 2732/4885HPGD 233/4885SMN1; SMN2 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.