Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035244 | 0.91 | HTR1A (0.33) | NR3C1ALDH1A1HTR1AADRA1DADRA1A | |
| SCHEMBL10035235 | 0.88 | ABCB1 (0.35) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10035239 | 0.87 | NR3C1 (0.31) | NR3C1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4584263 | 0.85 | NR3C1 (0.34) | NR3C1ALDH1A1HTR1AADRA1DADRA1A | |
| SCHEMBL24886350 | 0.84 | NR3C1 (0.37) | NR3C1ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL10035233 | 0.82 | ALDH1A1 (0.33) | NR3C1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL14570900 | 0.82 | SYK (0.34) | NR3C1 | |
| SCHEMBL10035242 | 0.81 | CRHR1 (0.33) | — | |
| SCHEMBL5549072 | 0.80 | NR3C1 (0.32) | NR3C1ALDH1A1 | |
| SCHEMBL14124742 | 0.80 | ABCB1 (0.33) | ALDH1A1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178695-B2 | Applying to unwanted plants or weeds; controlling broadleaf plants | BAYER CROPSCIENCE AG (DE) | 2012-05-15 | — | — | US | disclosed |
| US-20080254990-A1 | 4-(3-Aminobenzoyl)-1,3-dimethylpyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080254990-A1 | 4-(3-Aminobenzoyl)-1,3-dimethylpyrazoles and their use as herbicides | DDT, TH, ABAT | NR3C1 1717/4885ALDH1A1 135/4885HTR1A 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.