SCHEMBL10035660

SCHEMBL10035660

Cc1cc2ccccc2cc1-c1nc2c3ccccc3c3ccccc3c2n1-c1ccc(Oc2ccc(-n3c(-c4ccccc4O)nc(-c4ccccc4)c3-c3ccccc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MGAM O43451 6/20 0.38
GAA P10253 6/20 0.38
SI P14410 6/20 0.38
MGAM2 Q2M2H8 6/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
TOP2A P11388 3/20 0.36
TNK2 Q07912 1/20 0.35
FABP4 P15090 2/20 0.33
FABP5 Q01469 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10025664 0.94 BCHE (0.39) MGAMGAASIMGAM2BCHE
SCHEMBL10025663 0.90 BCHE (0.44) MGAMGAASIMGAM2BCHE
SCHEMBL667896 0.83 BCHE (0.46) MGAMGAASIMGAM2BCHE
SCHEMBL668731 0.77 BCHE (0.46) MGAMGAASIMGAM2BCHE
SCHEMBL12133010 0.77 MGAM (0.35) MGAMGAASIMGAM2BCHE
SCHEMBL24462147 0.74 DHFR (0.50) GAAMEN1KMT2A
SCHEMBL30714897 0.74 DHFR (0.50) GAAMEN1KMT2A
SCHEMBL668716 0.73 GAA (0.54) MGAMGAASIMGAM2BCHE
SCHEMBL31035781 0.73 BCHE (0.56) MGAMGAASIMGAM2BCHE
SCHEMBL668695 0.73 BCHE (0.62) MGAMGAASIMGAM2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120046472-A1 WHITE-EMITTING COMPOUNDS USING EXCITED-STATE INTRAMOLECULAR PROTON TRANSFER, ORGANIC ELECTROLUMINESCENT ELEMENT AND LASER MATERIAL USING THE SAME SNU R&DB FOUNDATION (KR) 2012-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046472-A1 WHITE-EMITTING COMPOUNDS USING EXCITED-STATE INTRAMOLECULAR PROTON TRANSFER, ORGANIC ELECTROLUMINESCENT ELEMENT AND LASER MATERIAL USING THE SAME ICMT, INCENP, TRMT1 MGAM 3678/4885GAA 2579/4885SI 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.