SCHEMBL10035883

SCHEMBL10035883

CCOC(=O)CCCCCOc1ccc2ccc3c(c2c1)C(C)(C)C(C)=N3

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 3/20 0.48
CYSLTR1 Q9Y271 3/20 0.48
FFAR1 O14842 1/20 0.48
PDE3B Q13370 2/20 0.45
PDE3A Q14432 2/20 0.45
P2RY12 Q9H244 1/20 0.44
PDK2 Q15119 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH2 P05091 2/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
BRD4 O60885 1/20 0.41
LTA4H P09960 1/20 0.39
PLA2G2A P14555 1/20 0.39
MTNR1A P48039 3/20 0.39
MTNR1B P49286 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10035880 0.89 MEN1 (0.45) CYSLTR2CYSLTR1PDE3BPDE3AP2RY12
SCHEMBL660896 0.84 PDK2 (0.52) CYSLTR2CYSLTR1FFAR1PDE3BPDE3A
SCHEMBL662124 0.71 PDK2 (0.47) FFAR1PDE3BPDE3AP2RY12PDK2
SCHEMBL9132945 0.70 CYSLTR2 (0.54) CYSLTR2CYSLTR1FFAR1PDE3BPDE3A
SCHEMBL4095329 0.69 FFAR1 (0.54) CYSLTR2CYSLTR1FFAR1PDE3BPDE3A
SCHEMBL14570538 0.69 MEN1 (0.59) CYSLTR2CYSLTR1FFAR1PDK2MEN1
SCHEMBL10203017 0.69 BRD4 (0.55) CYSLTR2CYSLTR1FFAR1PDE3BPDE3A
SCHEMBL15798175 0.69 CYSLTR2 (0.58) CYSLTR2CYSLTR1FFAR1PDK2ALDH2
SCHEMBL7632059 0.69 CYSLTR2 (0.64) CYSLTR2CYSLTR1FFAR1PDE3BPDE3A
SCHEMBL19474670 0.68 LTA4H (0.53) CYSLTR2CYSLTR1FFAR1PDK2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1981846-B1 MARKERS, METHOD FOR MANUFACTURING THEM AND THEIR APPLICATIONS LABORATOIRES SYNTH-INNOVE (FR) 2017-11-01 EP disclosed
US-20120045851-A1 LABELS, THEIR PRODUCTION PROCESS AND THEIR USES LABORATOIRES SYNTH-INNOVE (FR) 2012-02-23 US disclosed
US-20120045851-A1 LABELS, THEIR PRODUCTION PROCESS AND THEIR USES LABORATOIRES SYNTH-INNOVE (FR) 2012-02-23 US disclosed
US-8034626-B2 Labels, their production process and their uses LABORATOIRES SYNTH-INNOVE (FR) 2011-10-11 US disclosed
US-8034626-B2 Labels, their production process and their uses LABORATOIRES SYNTH-INNOVE (FR) 2011-10-11 US disclosed
US-20080318336-A1 Labels, Their Production Process And Their Uses LABORATOIRES SYNTH-INNOVE (FR) 2008-12-25 US disclosed
US-20080318336-A1 Labels, Their Production Process And Their Uses LABORATOIRES SYNTH-INNOVE (FR) 2008-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045851-A1 LABELS, THEIR PRODUCTION PROCESS AND THEIR USES HLCS, PFAS, CYBA CYSLTR2 2087/4885CYSLTR1 2263/4885FFAR1 3330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.