Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.37 |
| ▸ | S100A10 | P60903 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036670 | 0.93 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPK1TSHRCYP3A4MLYCD | |
| SCHEMBL10002094 | 0.84 | CYP3A4 (0.42) | SMN1; SMN2MAPK1TSHRCYP3A4MLYCD | |
| SCHEMBL31457316 | 0.83 | TSHR (0.52) | MAPK1TSHRCYP3A4PDE7AKDM4E | |
| SCHEMBL7187814 | 0.83 | TSHR (0.52) | MAPK1TSHRCYP3A4PDE7AKDM4E | |
| SCHEMBL1635164 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPK1TSHRCYP3A4MLYCD | |
| SCHEMBL10002081 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPK1TSHRCYP3A4MLYCD | |
| SCHEMBL1809687 | 0.75 | PDE7A (0.41) | SMN1; SMN2MAPK1TSHRCYP3A4PDE7A | |
| SCHEMBL10036534 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPK1TSHRCYP3A4KDM4E | |
| SCHEMBL10036587 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPK1TSHRKDM4EALDH1A1 | |
| SCHEMBL10036539 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPK1TSHRCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10384172-B2 | Composite membrane with multi-layered active layer | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2019-08-20 | — | — | US | disclosed |
| US-10293308-B2 | Antifouling and antimicrobial coatings for thin film composite membranes | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2019-05-21 | — | — | US | disclosed |
| US-20190015789-A1 | ANTIFOULING AND ANTIMICROBIAL COATINGS FOR THIN FILM COMPOSITE MEMBRANES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2019-01-17 | — | — | US | disclosed |
| US-20170144113-A1 | COMPOSITE MEMBRANE WITH MULTI-LAYERED ACTIVE LAYER | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-05-25 | — | — | US | disclosed |
| US-9561474-B2 | Composite membrane with multi-layered active layer | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-02-07 | — | — | US | disclosed |
| US-20170001151-A1 | ANTIFOULING AND ANTIMICROBIAL COATINGS FOR THIN FILM COMPOSITE MEMBRANES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-01-05 | — | — | US | disclosed |
| US-9504967-B2 | Composite membrane with multi-layered active layer | GLOBALFOUNDRIES INC. (KY) | 2016-11-29 | — | — | US | disclosed |
| EP-2398840-B1 | INTERFACIAL POLYMERIZATION METHODS FOR MAKING FLUOROALCOHOL-CONTAINING POLYAMIDES | IBM (US) | 2016-07-13 | — | — | EP | disclosed |
| US-20140353253-A1 | COMPOSITE MEMBRANE WITH MULTI-LAYERED ACTIVE LAYER | GLOBALFOUNDRIES U.S. INC. | 2014-12-04 | — | — | US | disclosed |
| US-8857629-B2 | Composite membrane with multi-layered active layer | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-10-14 | — | — | US | disclosed |
| US-20100216899-A1 | POLYAMIDE MEMBRANES WITH FLUOROALCOHOL FUNCTIONALITY | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2010-08-26 | — | — | US | disclosed |
| US-20100216899-A1 | POLYAMIDE MEMBRANES WITH FLUOROALCOHOL FUNCTIONALITY | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2010-08-26 | — | — | US | disclosed |
| US-7728103-B2 | Fluorine-containing polymerizable monomer and polymer compound using same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2010-06-01 | — | — | US | disclosed |
| US-7728103-B2 | Fluorine-containing polymerizable monomer and polymer compound using same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2010-06-01 | — | — | US | disclosed |
| US-7629434-B2 | Waterproofing; oil repellent; nonabsorber; heat resistance; weatherproofing; corrosion resistance; radiation transparent; photosensitivity; low refractive index and dielectrics | CENTRAL GLASS COMPANY, LIMITED (JP) | 2009-12-08 | — | — | US | disclosed |
| US-7629434-B2 | Waterproofing; oil repellent; nonabsorber; heat resistance; weatherproofing; corrosion resistance; radiation transparent; photosensitivity; low refractive index and dielectrics | CENTRAL GLASS COMPANY, LIMITED (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20090292104-A1 | Polyamides from a dianiline compound where one or both of the rings is o-substituted with a 2-hydroxyhexafluoropropyl group and a di- or tetracarboxylic acid; polyimides; polybenzoxazines; repellency, oil repellency, low water absorption; resistance to heat, oil, water, & corrosion; low refractive index | CENTRAL GLASS COMPANY, LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090292104-A1 | Polyamides from a dianiline compound where one or both of the rings is o-substituted with a 2-hydroxyhexafluoropropyl group and a di- or tetracarboxylic acid; polyimides; polybenzoxazines; repellency, oil repellency, low water absorption; resistance to heat, oil, water, & corrosion; low refractive index | CENTRAL GLASS COMPANY, LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20080234460-A1 | Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same | CENTRAL GLASS CO., LTD. (JP) | 2008-09-25 | — | — | US | disclosed |
| US-20080234460-A1 | Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same | CENTRAL GLASS CO., LTD. (JP) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234460-A1 | Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same | AFF2, FRG1, PFAS | SMN1; SMN2 1644/4885MAPK1 1210/4885TSHR 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.