Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28354889 | 0.89 | MAPT (0.40) | KDM4EALDH1A1SMN1; SMN2CA9CA12 | |
| SCHEMBL3179374 | 0.89 | — | — | |
| SCHEMBL3189139 | 0.82 | — | — | |
| SCHEMBL2555525 | 0.81 | MAPK14 (0.38) | ACHECYP19A1NQO2KDM4EALDH1A1 | |
| SCHEMBL2991243 | 0.81 | CA1 (0.33) | ACHEKDM4EALDH1A1CA9CA12 | |
| SCHEMBL31651724 | 0.81 | CA1 (0.33) | ACHEKDM4EALDH1A1CA9CA12 | |
| SCHEMBL27277668 | 0.81 | SMN1; SMN2 (0.41) | KDM4EALDH1A1SMN1; SMN2MAPTTUBB4A | |
| SCHEMBL8882946 | 0.78 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPT | |
| SCHEMBL317432 | 0.78 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPK14 | |
| SCHEMBL191237 | 0.78 | MAPK14 (0.33) | ACHEKDM4EALDH1A1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746350-A | Anhydridization synthesis method in pyridine hydrochloride production | 安徽金禾实业股份有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-110746350-A | Anhydridization synthesis method in pyridine hydrochloride production | 安徽金禾实业股份有限公司 | 2020-02-04 | — | — | CN | disclosed |
| CN-110746350-A | Anhydridization synthesis method in pyridine hydrochloride production | 安徽金禾实业股份有限公司 | 2020-02-04 | — | — | CN | disclosed |
| CN-101875629-B | Industrial preparation method of pantoprazole intermediate pyridine hydrochloride | NANJING YUANHUA TECHNOLOGY CONSULTATION CO LTD | 2013-03-06 | — | — | CN | disclosed |
| US-20120107248-A1 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-05-03 | — | — | US | disclosed |
| US-20120107248-A1 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-05-03 | — | — | US | disclosed |
| WO-2011005609-A2 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-01-13 | — | — | WO | disclosed |
| WO-2011005609-A2 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-01-13 | — | — | WO | disclosed |
| CN-101875629-A | Industrial preparation method of pantoprazole intermediate pyridine hydrochloride | NANJING YUANHUA TECHNOLOGY CONSULTATION CO LTD | 2010-11-03 | — | — | CN | disclosed |
| CN-1029973-C | Process for the preparation of substituted thienoimidazole derivatives | HOECHST AG (DE) | 1995-10-11 | — | — | CN | disclosed |
| CN-1011969-B | Benzimidazole derivatives and their preparation | BYK GULDEN LOMBERG CHEM FAB (DE) | 1991-03-13 | — | — | CN | disclosed |
| CN-1032340-A | The Thienoimidazole derivatives that replaces, its preparation method and contain the pharmaceutical preparation of this derivative and they are as the purposes of gastric acid secretion inhibitor | HOECHST AG (DE) | 1989-04-12 | — | — | CN | disclosed |
| US-4758579-A | e.g. pantoprazole or pantoprazole sodium | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4686230-A | Picoline derivative useful as gastric acid secretion inhibitors | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1987-08-11 | — | — | US | disclosed |
| CN-85104684-A | The dialkoxy pyridine, their preparation method, purposes and contain their medicine | — | 1986-12-31 | — | — | CN | disclosed |
| US-4523015-A | Process and nitroaminopyrimidone intermediates for histamine H2 -antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-11 | — | — | US | disclosed |
| EP-0004793-B1 | 2-NITRO AMINOPYRIMIDONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE TO PREPARE 2-AMINOPYRIMIDONE DERIVATIVES WHICH HAVE HISTAMINE H2-ANTAGONIST ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-12-30 | — | — | EP | disclosed |
| US-4227000-A | Intermediates in the process for making histamine antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-07 | — | — | US | disclosed |
| EP-0004793-A2 | 2-nitro aminopyrimidone derivatives, a process for their preparation and their use to prepare 2-aminopyrimidone derivatives which have histamine H2-antagonist activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107248-A1 | IMAGING GASTROINTESTINAL VOLUMES AND MOTILITY | SLC10A2, KCNN3, KCNN2 | ACHE 110/4885CYP19A1 4219/4885NQO2 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.