Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297897 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10L3MBTL1TSHR | |
| SCHEMBL3183642 | 0.87 | — | — | |
| SCHEMBL1003702 | 0.78 | ACHE (0.37) | ALDH1A1KDM4EMAPK14 | |
| SCHEMBL30147933 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL712432 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL13729104 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10L3MBTL1TSHR | |
| SCHEMBL4264731 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL10668912 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10L3MBTL1TSHR | |
| SCHEMBL8882728 | 0.73 | POLB (0.42) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL191237 | 0.72 | MAPK14 (0.33) | ALDH1A1KDM4EMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107129466-B | Synthesis method of 4-chloro-3-methoxy-2-methylpyridine-N-oxide | 滁州学院 | 2020-11-13 | — | — | CN | claimed |
| EP-1335913-B1 | A PROCESS FOR THE PREPARATION OF PANTOPRAZOLE AND INTERMEDIATES THEREFOR | DINAMITE DIPHARMA SPA (IT) | 2004-09-08 | — | — | EP | claimed |
| US-20040049044-A1 | Process for the preparation of pantoprazole and intermediates therefor | DINAMITE DIPHARMA (DIPHARMA S.P.A.) (IT) | 2004-03-11 | — | — | US | claimed |
| EP-1335913-A1 | A PROCESS FOR THE PREPARATION OF PANTOPRAZOLE AND INTERMEDIATES THEREFOR | Dinamite Dipharma S.p.A. (in abbreviated form Dipharma S.p.A.) (IT) | 2003-08-20 | — | — | EP | claimed |
| WO-2002028852-A1 | A PROCESS FOR THE PREPARATION OF PANTOPRAZOLE AND INTERMEDIATES THEREFOR | DINAMITE DIPHARMA (IT) | 2002-04-11 | — | — | WO | claimed |
| US-20250163078-A1 | IMIDAZOPYRIDAZINE DERIVATIVE, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2025-05-22 | — | — | US | disclosed |
| EP-4484433-A1 | IMIDAZOPYRIDAZINE DERIVATIVE, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2025-01-01 | — | — | EP | disclosed |
| CN-116693555-A | Imidazopyridazine derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023160475-A1 | IMIDAZOPYRIDAZINE DERIVATIVE, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2023-08-31 | — | — | WO | disclosed |
| CN-107129466-B | Synthesis method of 4-chloro-3-methoxy-2-methylpyridine-N-oxide | 滁州学院 | 2020-11-13 | — | — | CN | disclosed |
| CN-107129466-B | Synthesis method of 4-chloro-3-methoxy-2-methylpyridine-N-oxide | 滁州学院 | 2020-11-13 | — | — | CN | disclosed |
| CN-107129466-B | Synthesis method of 4-chloro-3-methoxy-2-methylpyridine-N-oxide | 滁州学院 | 2020-11-13 | — | — | CN | disclosed |
| US-5922720-A | PHARMACEUTICAL FOR USE IN TREATMENT OF DISEASES BASED ON HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5859030-A | Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-01-12 | — | — | US | disclosed |
| US-5773451-A | BACTERICIDES FOR HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-06-30 | — | — | US | disclosed |
| US-5658933-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |
| US-5587389-A | Substituted heteroarylaklylthiopyridines for controlling helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| US-5430042-A | Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use | AKTIEBOLAGET ASTRA (SE) | 1995-07-04 | — | — | US | disclosed |
| EP-0593463-A1 | DIALKOXY-PYRIDINYL-BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | AKTIEBOLAGET ASTRA (SE) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019712-A1 | DIALKOXY-PYRIDINYL-BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | AKTIEBOLAGET ASTRA (SE) | 1991-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163078-A1 | IMIDAZOPYRIDAZINE DERIVATIVE, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | CYP4A11, CYP4F11, SLC6A11 | ALDH1A1 437/4885KDM4E 3724/4885HSD17B10 1558/4885 |
| US-20040049044-A1 | Process for the preparation of pantoprazole and intermediates therefor | CYP4F11, CYP2F1, POR | ALDH1A1 301/4885KDM4E 4077/4885HSD17B10 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.