SCHEMBL10037040

SCHEMBL10037040

CCCCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)OCC(O)CC

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.73
DGKA P23743 1/20 0.64
LPAR1 Q92633 7/20 0.57
LPAR4 Q99677 3/20 0.57
LPAR2 Q9HBW0 3/20 0.57
LPAR3 Q9UBY5 3/20 0.57
ENPP2 Q13822 2/20 0.57
LPAR5 Q9H1C0 2/20 0.57
CES2 O00748 1/20 0.57
LPAR6 P43657 1/20 0.57
TRPV1 Q8NER1 1/20 0.57
MGLL Q99685 1/20 0.56
ALDH1A1 P00352 2/20 0.55
MAPT P10636 2/20 0.55
CNR1 P21554 2/20 0.55
GPR55 Q9Y2T6 1/20 0.55
THRB P10828 1/20 0.55
HPGD P15428 1/20 0.51
CNR2 P34972 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28064656 0.93 FAAH (0.76) FAAHDGKALPAR1LPAR4LPAR2
SCHEMBL9905934 0.90 FAAH (0.90) FAAHDGKALPAR1MGLLALDH1A1
SCHEMBL23268626 0.90 FAAH (0.90) FAAHDGKALPAR1MGLLALDH1A1
SCHEMBL9905952 0.89 FAAH (0.70) FAAHDGKALPAR1LPAR4LPAR2
SCHEMBL1899258 0.88 FAAH (0.82) FAAHDGKALPAR1LPAR4LPAR2
SCHEMBL15516648 0.88 FAAH (0.86) FAAHDGKALPAR1LPAR4LPAR2
SCHEMBL19821305 0.88 DGKA (0.81) FAAHDGKALPAR1LPAR4LPAR2
1-Monoolein SCHEMBL1197776 0.88 DGKA (0.81) FAAHDGKALPAR1LPAR4LPAR2
SCHEMBL18623397 0.88 DGKA (0.81) FAAHDGKALPAR1LPAR4LPAR2
1-Monoolein SCHEMBL18623398 0.88 DGKA (0.81) FAAHDGKALPAR1LPAR4LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329747-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof Centro de Recherche sur les Biotechnologies Marines (CA) 2012-12-11 US disclosed
US-8119690-B2 Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) 2012-02-21 US disclosed
US-20100160261-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF SCF PHARMA INC. (CA) 2010-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160261-A1 POLYUNSATURATED FATTY ACID MONOGLYCERIDES, DERIVATIVES, AND USES THEREOF FASN, MGLL, FADS1 FAAH 225/4885DGKA 36/4885LPAR1 194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.