SCHEMBL10037346

SCHEMBL10037346

O=C1c2c(-c3cccs3)sc(-c3ccc(-c4ccc(-c5sc(-c6cccs6)c6c5C(=O)C(F)(F)C6=O)s4)s3)c2C(=O)C1(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.41
LTA4H P09960 1/20 0.39
ALDH1A1 P00352 6/20 0.37
LMNA P02545 3/20 0.37
KDM4E B2RXH2 3/20 0.37
GAA P10253 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
GLA P06280 1/20 0.37
MAPT P10636 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
HPGD P15428 3/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
NFKB1 P19838 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10037342 0.94 MEN1 (0.38) DPP4LTA4HALDH1A1LMNAKDM4E
SCHEMBL10037344 0.88 LTA4H (0.33) DPP4LTA4HALDH1A1LMNAKDM4E
SCHEMBL10037354 0.78 PTP4A3 (0.33) LMNAL3MBTL1MAPTMEN1KMT2A
SCHEMBL10037345 0.78 HSD17B1 (0.40) ALDH1A1KDM4EMEN1KMT2ANPC1
SCHEMBL10037357 0.73 SNCA (0.33) ALDH1A1LMNAKDM4EL3MBTL1MAPT
SCHEMBL10037353 0.73
SCHEMBL12973008 0.73
SCHEMBL29177041 0.73 SLC6A11 (0.41) DPP4ALDH1A1LMNAKDM4EGAA
SCHEMBL4319170 0.71 MEN1 (0.47) DPP4LTA4HALDH1A1LMNAKDM4E
SCHEMBL12973003 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114956-B2 Polymer having unit obtained by condensation of difluorocyclopentanedione ring and aromatic ring, organic thin film using the same, and organic thin film device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8114956-B2 Polymer having unit obtained by condensation of difluorocyclopentanedione ring and aromatic ring, organic thin film using the same, and organic thin film device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-20100084640-A1 POLYMER HAVING UNIT OBTAINED BY CONDENSATION OF DIFLUOROCYCLOPENTANEDIONE RING AND AROMATIC RING, ORGANIC THIN FILM USING THE SAME, AND ORGANIC THIN FILM DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
US-20100084640-A1 POLYMER HAVING UNIT OBTAINED BY CONDENSATION OF DIFLUOROCYCLOPENTANEDIONE RING AND AROMATIC RING, ORGANIC THIN FILM USING THE SAME, AND ORGANIC THIN FILM DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-2123690-A1 POLYMER HAVING UNIT OBTAINED BY CONDENSATION OF DIFLUOROCYCLOPENTANEDIONE RING AND AROMATIC RING, ORGANIC THIN FILM USING THE SAME, AND ORGANIC THIN FILM DEVICE Sumitomo Chemical Company, Limited (JP) 2009-11-25 EP disclosed