SCHEMBL10037360

SCHEMBL10037360

O=C1CC(=O)c2c(-c3cccs3)sc(-c3cccs3)c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
TYMP P19971 1/20 0.38
DPP4 P27487 1/20 0.37
LTK P29376 1/20 0.37
CDK5 Q00535 1/20 0.37
MST1R Q04912 1/20 0.37
DYRK1A Q13627 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37
ALDH1A1 P00352 10/20 0.36
HPGD P15428 8/20 0.36
KDM4E B2RXH2 6/20 0.36
HSD17B10 Q99714 3/20 0.36
ALPL P05186 1/20 0.36
MAPT P10636 5/20 0.36
LMNA P02545 4/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
GAA P10253 3/20 0.36
GLA P06280 1/20 0.36
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4319170 0.79 MEN1 (0.47) MEN1KMT2ATYMPDPP4ALDH1A1
SCHEMBL29177041 0.77 SLC6A11 (0.41) MEN1KMT2ATYMPDPP4LTK
SCHEMBL21969742 0.74 DPP4 (0.39) MEN1KMT2ATYMPDPP4CLK4
SCHEMBL12788687 0.74 MEN1 (0.38) MEN1KMT2ATYMPDPP4ALDH1A1
SCHEMBL10037342 0.74 MEN1 (0.38) MEN1KMT2ATYMPDPP4LTK
SCHEMBL650323 0.73 MEN1 (0.46) MEN1KMT2ADPP4ALDH1A1HPGD
SCHEMBL10037346 0.69 DPP4 (0.41) MEN1KMT2ATYMPDPP4ALDH1A1
SCHEMBL7132180 0.69 MEN1 (0.46) MEN1KMT2ADPP4ALDH1A1HPGD
SCHEMBL2760838 0.69 MEN1 (0.46) MEN1KMT2ADPP4ALDH1A1HPGD
SCHEMBL1086309 0.69 MEN1 (0.55) MEN1KMT2ADPP4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114956-B2 Polymer having unit obtained by condensation of difluorocyclopentanedione ring and aromatic ring, organic thin film using the same, and organic thin film device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-8114956-B2 Polymer having unit obtained by condensation of difluorocyclopentanedione ring and aromatic ring, organic thin film using the same, and organic thin film device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-14 US disclosed
US-20100084640-A1 POLYMER HAVING UNIT OBTAINED BY CONDENSATION OF DIFLUOROCYCLOPENTANEDIONE RING AND AROMATIC RING, ORGANIC THIN FILM USING THE SAME, AND ORGANIC THIN FILM DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
US-20100084640-A1 POLYMER HAVING UNIT OBTAINED BY CONDENSATION OF DIFLUOROCYCLOPENTANEDIONE RING AND AROMATIC RING, ORGANIC THIN FILM USING THE SAME, AND ORGANIC THIN FILM DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-2123690-A1 POLYMER HAVING UNIT OBTAINED BY CONDENSATION OF DIFLUOROCYCLOPENTANEDIONE RING AND AROMATIC RING, ORGANIC THIN FILM USING THE SAME, AND ORGANIC THIN FILM DEVICE Sumitomo Chemical Company, Limited (JP) 2009-11-25 EP disclosed