SCHEMBL21969742

SCHEMBL21969742

CN1C(=O)c2c(-c3cccs3)sc(-c3cccs3)c2C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.39
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 5/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
USP2 O75604 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
CASP1 P29466 2/20 0.37
CASP7 P55210 2/20 0.37
HIF1A Q16665 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12019932 0.80 MAOB (0.41) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL2009284 0.78 ALDH1A1 (0.43) ALDH1A1KDM4EGAACYP3A4HIF1A
SCHEMBL14716539 0.78 ALDH1A1 (0.43) ALDH1A1KDM4EGAACYP3A4HIF1A
SCHEMBL4319170 0.76 MEN1 (0.47) DPP4ALDH1A1KDM4EMEN1KMT2A
SCHEMBL29177041 0.74 SLC6A11 (0.41) DPP4ALDH1A1KDM4EMEN1KMT2A
SCHEMBL10037360 0.74 MEN1 (0.40) DPP4ALDH1A1KDM4EMEN1KMT2A
SCHEMBL25831625 0.74 MEN1 (0.38) DPP4ALDH1A1KDM4EMEN1KMT2A
SCHEMBL15979504 0.73 MAPT (0.37) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL15031170 0.72 ADK (0.49) ALDH1A1MAPTLMNARAB9A
SCHEMBL1498244 0.72 ALDH1A1 (0.36) ALDH1A1KDM4EMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11299581-B2 Conjugated polymer and application thereof RAYNERGY TEK INC. (TW) 2022-04-12 US disclosed
US-20200140605-A1 CONJUGATED POLYMER AND APPLICATION THEREOF RAYNERGY TEK INC. (TW) 2020-05-07 US disclosed