SCHEMBL10038533

SCHEMBL10038533

Cc1ccc(-c2nnc(-c3ccc(-c4ccccc4)cc3)o2)cc1

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 16/20 0.96
RAB9A P51151 16/20 0.96
SMN1; SMN2 Q16637 12/20 0.96
HPGD P15428 8/20 0.96
NFKB1 P19838 2/20 0.96
NFKB2 Q00653 2/20 0.96
RELA Q04206 2/20 0.96
POLB P06746 1/20 0.96
TSHR P16473 3/20 0.67
ALDH1A1 P00352 5/20 0.66
HSD17B10 Q99714 2/20 0.66
CYP1A2 P05177 1/20 0.66
CYP3A4 P08684 1/20 0.66
CYP2C9 P11712 1/20 0.66
KDM4E B2RXH2 6/20 0.66
MAPT P10636 3/20 0.66
GLA P06280 1/20 0.66
ALOX15 P16050 1/20 0.66
KMT2A Q03164 4/20 0.64
MEN1 O00255 3/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21673239 1.00 NPC1 (0.96) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL14461284 1.00 NPC1 (0.96) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL14818889 0.98 NPC1 (1.00) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL762284 0.98 NPC1 (1.00) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL13231671 0.91 NPC1 (0.79) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL14461283 0.89 NPC1 (0.77) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL13134518 0.89 NPC1 (0.77) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL22858502 0.89 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL46424 0.89 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL120253 0.89 NPC1 (0.83) NPC1RAB9ASMN1; SMN2HPGDNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024642-A Scintillation resin with strontium-90 separation and detection functions and preparation method and application thereof 兰州大学 2023-11-10 CN claimed
CN-117024642-A Scintillation resin with strontium-90 separation and detection functions and preparation method and application thereof 兰州大学 2023-11-10 CN disclosed
EP-4207325-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREFOR BOE Technology Group Co., Ltd. (CN) 2023-07-05 EP disclosed
EP-2674418-B1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO (JP) 2021-01-06 EP disclosed
US-9960356-B2 Organic electroluminescence device, lighting equipment and display device Konica Minolta, Inc. (JP) 2018-05-01 US disclosed
US-9944629-B2 Material for organic electroluminescent element, organic electroluminescent element, illumination device, and display device Konica Minolta, Inc. (JP) 2018-04-17 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-20170309839-A1 IRIDIUM COMPLEX, METHOD FOR PRODUCING IRIDIUM COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE KONICA MINOLTA INC (JP) 2017-10-26 US disclosed
US-9748501-B2 Iridium complex, method for producing iridium complex, organic electroluminescent element, display device, and lighting device Konica Minolta, Inc. (JP) 2017-08-29 US disclosed
US-9673405-B2 Organic electroluminescent device, display apparatus, and lighting apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2017-06-06 US disclosed
US-8053024-B2 Method for manufacturing organic electroluminescent device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-08 US disclosed
US-7897962-B2 Organic electroluminescence device, lighting device, and display having a reactive organic compound KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-01 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20100108991-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-05-06 US disclosed
US-7705114-B2 Method for producing polymer organic electronic material, polymer organic electronic material, and organic electroluminescent device FUJI XEROX CO., LTD. (JP) 2010-04-27 US disclosed
US-20090081357-A1 METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENT DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-03-26 US disclosed
US-7431996-B2 Polyester resin, functional device and organic electroluminescent device using polyester resin, and method of manufacturing organic electroluminescent device FUJI XEROX CO., LTD. (JP) 2008-10-07 US disclosed
US-7264891-B2 Organic electroluminescent device and organic electroluminescent compound thereof RIT DISPLAY CORPORATION (TW) 2007-09-04 US disclosed
US-7186468-B2 Organic electro-luminescent display device and method for manufacturing the same KABUSHIKI KAISHA TOSHIBA (JP) 2007-03-06 US disclosed
US-4014871-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170309839-A1 IRIDIUM COMPLEX, METHOD FOR PRODUCING IRIDIUM COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE EED, SNW1, AP2M1 NPC1 4309/4885RAB9A 3099/4885SMN1; SMN2 1448/4885
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL NPC1 4745/4885RAB9A 2444/4885SMN1; SMN2 4070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.