SCHEMBL762284

SCHEMBL762284

Cc1ccc(-c2nnc(-c3ccccc3)o2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 16/20 1.00
RAB9A P51151 16/20 1.00
SMN1; SMN2 Q16637 12/20 1.00
HPGD P15428 8/20 1.00
NFKB1 P19838 2/20 1.00
NFKB2 Q00653 2/20 1.00
RELA Q04206 2/20 1.00
POLB P06746 1/20 1.00
TSHR P16473 3/20 0.69
ALDH1A1 P00352 5/20 0.68
HSD17B10 Q99714 2/20 0.68
CYP1A2 P05177 1/20 0.68
CYP3A4 P08684 1/20 0.68
CYP2C9 P11712 1/20 0.68
KDM4E B2RXH2 6/20 0.66
KMT2A Q03164 4/20 0.66
MEN1 O00255 3/20 0.66
MAPT P10636 3/20 0.66
NPSR1 Q6W5P4 2/20 0.66
GAA P10253 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14818889 1.00 NPC1 (1.00) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL14461284 0.98 NPC1 (0.96) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL21673239 0.98 NPC1 (0.96) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL10038533 0.98 NPC1 (0.96) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL120253 0.91 NPC1 (0.83) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL6015198 0.91 NPC1 (0.83) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL11736620 0.89 RAB9A (0.79) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL13231671 0.89 NPC1 (0.79) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL4343181 0.89 NPC1 (0.94) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL13589152 0.88 NPC1 (0.78) NPC1RAB9ASMN1; SMN2HPGDNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11508927-B2 Organic electroluminescence device, preparation method thereof and display apparatus KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2022-11-22 US disclosed
US-10827753-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2020-11-10 US disclosed
US-10749128-B2 Depositable ion organic function material and use thereof in organic electroluminescent device KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2020-08-18 US disclosed
US-20200203652-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, PREPARATION METHOD THEREOF AND DISPLAY APPARATUS KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2020-06-25 US disclosed
US-20190343120-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-11-14 US disclosed
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-10-31 US disclosed
US-10375958-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2019-08-13 US disclosed
US-20190021325-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES MONSANTO TECHNOLOGY LLC (US) 2019-01-24 US disclosed
CN-108739825-A Composition for controlling nematode and method 孟山都技术有限责任公司 2018-11-06 CN disclosed
US-10112930-B2 Compositions and methods for controlling nematodes MONSANTO TECHNOLOGY LLC (US) 2018-10-30 US disclosed
US-7166859-B2 Organic semiconductor transistor element, semiconductor device using the same, and process for producing the semiconductor device FUJI XEROX CO., LTD. (JP) 2007-01-23 US disclosed
US-7166859-B2 Organic semiconductor transistor element, semiconductor device using the same, and process for producing the semiconductor device FUJI XEROX CO., LTD. (JP) 2007-01-23 US disclosed
EP-0006171-B1 STILBENE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1982-07-28 EP disclosed
EP-0006176-B1 STILBENE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-06 EP disclosed
EP-0008123-A1 Diamino-1,3,5-triazinylstilbene compounds, process for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1980-02-20 EP disclosed
EP-0006171-A1 Stilbene compounds, process for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-09 EP disclosed
EP-0006176-A1 Stilbene compounds, process for their preparation and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-09 EP disclosed
US-4113937-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1978-09-12 US disclosed
US-4032503-A TRIAZOLE RING CIBA-GEIGY CORPORATION (US) 1977-06-28 US disclosed
US-4014871-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10112930-B2 Compositions and methods for controlling nematodes NOP2, ATL3, CYCS NPC1 2871/4885RAB9A 3412/4885SMN1; SMN2 913/4885
US-10827753-B2 Compositions and methods for controlling nematodes NOP2, ATL3, CYCS NPC1 2871/4885RAB9A 3412/4885SMN1; SMN2 913/4885
US-20190021325-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES NOP2, ATL3, CYCS NPC1 2871/4885RAB9A 3412/4885SMN1; SMN2 913/4885
US-20190343120-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES NOP2, ATL3, CYCS NPC1 2871/4885RAB9A 3412/4885SMN1; SMN2 913/4885
US-10749128-B2 Depositable ion organic function material and use thereof in organic electroluminescent device OCIAD1, OCIAD2, OXA1L NPC1 905/4885RAB9A 2721/4885SMN1; SMN2 2962/4885
US-10375958-B2 Compositions and methods for controlling nematodes NOP2, ATL3, CYCS NPC1 2871/4885RAB9A 3412/4885SMN1; SMN2 913/4885
US-20190327967-A1 COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES NOP2, ATL3, CYCS NPC1 2871/4885RAB9A 3412/4885SMN1; SMN2 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.