SCHEMBL46424

SCHEMBL46424

c1ccc(-c2ccc(-c3nnc(-c4ccccc4)o3)cc2)cc1

nearest known ligand 0.90

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 15/20 0.90
RAB9A P51151 15/20 0.90
SMN1; SMN2 Q16637 9/20 0.90
HPGD P15428 7/20 0.79
ALDH1A1 P00352 5/20 0.79
KDM4E B2RXH2 4/20 0.79
HSD17B10 Q99714 2/20 0.79
GLA P06280 1/20 0.79
MAPT P10636 1/20 0.79
ALOX15 P16050 1/20 0.79
NFKB1 P19838 2/20 0.75
NFKB2 Q00653 2/20 0.75
RELA Q04206 2/20 0.75
POLB P06746 1/20 0.75
MEN1 O00255 1/20 0.75
KMT2A Q03164 1/20 0.75
ATAD2 Q6PL18 1/20 0.71
GAA P10253 1/20 0.68
CA1 P00915 2/20 0.66
CA2 P00918 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22858502 1.00 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL74999 1.00 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL522555 1.00 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL1105099 0.97 NPC1 (0.85) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL4343181 0.97 NPC1 (0.94) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL46426 0.95 NPC1 (1.00) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL12306750 0.91 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL12765574 0.91 RAB9A (0.76) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL12111793 0.91 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL19391492 0.91 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 975 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12581795-B2 Display device and method for manufacturing same SHARP KABUSHIKI KAISHA (JP) 2026-03-17 US claimed
US-12495665-B2 Display device having carrier blocking section between pixels SHARP KABUSHIKI KAISHA (JP) 2025-12-09 US claimed
US-12129414-B2 Defect-resistant plastic scintillation radiation detector compositions and fabrication methods LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2024-10-29 US claimed
CN-118265372-A Display substrate, manufacturing method thereof and display device 京东方科技集团股份有限公司 2024-06-28 CN claimed
CN-112018267-B Display panel, display device and preparation method 京东方科技集团股份有限公司 2024-04-05 CN claimed
CN-110655922-B Using In 3+ Wavelength tuning of ZnSe quantum dots with salts as dopants 昭荣化学工业株式会社 2024-02-27 CN claimed
US-11914085-B2 Plastic scintillator based on an organic polyaddition product TARGET SYSTEMELEKTRONIK GMBH & CO. KG (DE) 2024-02-27 US claimed
US-20230389392-A1 DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME SHARP KABUSHIKI KAISHA (JP) 2023-11-30 US claimed
CN-116940197-A Light emitting diode and preparation method thereof TCL科技集团股份有限公司 2023-10-24 CN claimed
US-20230309334-A1 DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME SHARP KABUSHIKI KAISHA (JP) 2023-09-28 US claimed
EP-0831676-A2 Organic electroluminescent element with exciplex Philips Patentverwaltung GmbH (DE) 1998-03-25 EP claimed
US-5529869-A IMPROVED ELECTRICAL CHARGE ACCEPTANCE AND CHARGE RETENTION ABILITY HEWLETT-PACKARD COMPANY (US) 1996-06-25 US claimed
EP-0697744-A1 Organic electroluminescent device Philips Patentverwaltung GmbH (DE) 1996-02-21 EP claimed
US-5308544-A A solution of naphthalene, a fluorescent compound and a radioactive beta emitter BECKMAN INSTRUMENTS, INC. (US) 1994-05-03 US claimed
WO-1991011735-A1 SCINTILLATION MEDIUM AND METHOD E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-08 WO claimed
US-4997597-A Solid-state radioluminescent compositions THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1991-03-05 US claimed
US-4758488-A Stabilized polysilylenes and imaging members therewith XEROX CORPORATION (US) 1988-07-19 US claimed
US-4728796-A Method for ionization of polymers MEDICAL COLLEGE OF WISCONSIN (US) 1988-03-01 US claimed
US-4594179-A Activation, intramolecular rearrangement THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-06-10 US claimed
US-4292527-A Radiation detection system THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1981-09-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12581795-B2 Display device and method for manufacturing same EPHA4, NECTIN4, L1CAM NPC1 2199/4885RAB9A 1568/4885SMN1; SMN2 4155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.