SCHEMBL10038538

SCHEMBL10038538

c1ccc(-c2ccccc2-c2ccc3c(c2)c2ncccc2n3-c2cccc(-c3cccc4c3oc3ccc(-n5c6ccc(-c7ccccc7-c7ccccn7)cc6c6ncccc65)cc34)c2)nc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.36
GRM5 P41594 14/20 0.36
ALOX5 P09917 1/20 0.35
MAPK14 Q16539 1/20 0.32
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5028434 0.96 ALOX5 (0.35) PRKDCGRM5ALOX5MAPK14
SCHEMBL5028237 0.91 ALOX5 (0.32) PRKDCALOX5MAPK14
SCHEMBL5028299 0.91 MAPK14 (0.32) PRKDCGRM5ALOX5MAPK14
SCHEMBL13471416 0.91 GRM5 (0.34) PRKDCGRM5MAPK14
SCHEMBL17264917 0.91 MAPK14 (0.33) PRKDCGRM5MAPK14
SCHEMBL16606295 0.91 MAPK14 (0.33) PRKDCGRM5MAPK14
SCHEMBL5031126 0.91 MAPK14 (0.34) GRM5MAPK14
SCHEMBL16919802 0.90 MAPK14 (0.32) PRKDCALOX5MAPK14
SCHEMBL21365316 0.90 NPC1 (0.34) GRM5ALOX5MAPK14
SCHEMBL12396561 0.90 NPC1 (0.34) GRM5ALOX5MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10468610-B2 Isomer-mixture metal complex composition, organic electroluminescent element, illuminator, and display device Konica Minolta, Inc. (JP) 2019-11-05 US disclosed
US-10347850-B2 Organic electroluminescent element, lighting device and display device Konica Minolta, Inc. (JP) 2019-07-09 US disclosed
US-10177322-B2 Iridium complex, method for producing iridium complex, organic electroluminescent element, display device, and lighting device Konica Minolta, Inc. (JP) 2019-01-08 US disclosed
US-9960356-B2 Organic electroluminescence device, lighting equipment and display device Konica Minolta, Inc. (JP) 2018-05-01 US disclosed
US-9960356-B2 Organic electroluminescence device, lighting equipment and display device Konica Minolta, Inc. (JP) 2018-05-01 US disclosed
US-9944629-B2 Material for organic electroluminescent element, organic electroluminescent element, illumination device, and display device Konica Minolta, Inc. (JP) 2018-04-17 US disclosed
US-9944629-B2 Material for organic electroluminescent element, organic electroluminescent element, illumination device, and display device Konica Minolta, Inc. (JP) 2018-04-17 US disclosed
US-20170309839-A1 IRIDIUM COMPLEX, METHOD FOR PRODUCING IRIDIUM COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE KONICA MINOLTA INC (JP) 2017-10-26 US disclosed
US-20170309839-A1 IRIDIUM COMPLEX, METHOD FOR PRODUCING IRIDIUM COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE KONICA MINOLTA INC (JP) 2017-10-26 US disclosed
US-9748501-B2 Iridium complex, method for producing iridium complex, organic electroluminescent element, display device, and lighting device Konica Minolta, Inc. (JP) 2017-08-29 US disclosed
EP-2930762-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-10-14 EP disclosed
US-20150207085-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-07-23 US disclosed
US-20150207085-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-07-23 US disclosed
US-20150179958-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-06-25 US disclosed
US-20150179958-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-06-25 US disclosed
US-9040975-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2015-05-26 US disclosed
US-9040975-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2015-05-26 US disclosed
US-20130099216-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-25 US disclosed
US-20130099216-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-25 US disclosed
US-20120018714-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY APPARATUS, AND LIGHTING APPARATUS KONICA MINOLTA HOLDINGS, INC. (JP) 2012-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10468610-B2 Isomer-mixture metal complex composition, organic electroluminescent element, illuminator, and display device EMC2, ELP1, EMC1 PRKDC 4191/4885GRM5 820/4885ALOX5 975/4885
US-10177322-B2 Iridium complex, method for producing iridium complex, organic electroluminescent element, display device, and lighting device EED, SNW1, AP2M1 PRKDC 2772/4885GRM5 1749/4885ALOX5 1708/4885
US-20170309839-A1 IRIDIUM COMPLEX, METHOD FOR PRODUCING IRIDIUM COMPLEX, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE EED, SNW1, AP2M1 PRKDC 2772/4885GRM5 1749/4885ALOX5 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.