SCHEMBL5028434

SCHEMBL5028434

c1ccc(-n2c3ccc(-c4cccc5c4oc4ccc(-n6c7ccc(-c8ccccc8-c8ccccn8)cc7c7ncccc76)cc45)cc3c3ncccc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
PRKDC P78527 3/20 0.35
GRM5 P41594 1/20 0.34
MAPK14 Q16539 1/20 0.32
PTPRF P10586 3/20 0.31
PTPN2 P17706 3/20 0.31
PTPN1 P18031 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10038538 0.96 PRKDC (0.36) ALOX5PRKDCGRM5MAPK14
SCHEMBL5029061 0.93 GRM5 (0.34) GRM5MAPK14
SCHEMBL12925698 0.93 ALOX5 (0.39) ALOX5PRKDCPTPRFPTPN2PTPN1
SCHEMBL19039699 0.92 KDM4E (0.33) GRM5MAPK14
SCHEMBL5028237 0.91 ALOX5 (0.32) ALOX5PRKDCMAPK14
SCHEMBL5028299 0.91 MAPK14 (0.32) ALOX5PRKDCGRM5MAPK14
SCHEMBL17264917 0.91 MAPK14 (0.33) PRKDCGRM5MAPK14
SCHEMBL16606295 0.91 MAPK14 (0.33) PRKDCGRM5MAPK14
SCHEMBL5031126 0.91 MAPK14 (0.34) GRM5MAPK14
SCHEMBL5028305 0.91 GRM5 (0.31) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190288219-A1 ORGANIC ELECTROLUMINESCENT ELEMENT MERCK PATENT GMBH (DE) 2019-09-19 US disclosed
US-9257651-B2 Organic electroluminescence element and method for manufacturing organic electroluminescence element KONICA MINOLTA HOLDINGS, INC. (JP) 2016-02-09 US disclosed
US-20130119360-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME MERCK PATENT GMBH (DE) 2013-05-16 US disclosed
US-20130087778-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENCE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-11 US disclosed
US-20130087778-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENCE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-11 US disclosed
US-8367224-B2 Organic electroluminescence element, new compound for the same, display device and lighting device using the same KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-05 US disclosed
EP-2453496-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta Holdings, Inc. (JP) 2012-05-16 EP disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190288219-A1 ORGANIC ELECTROLUMINESCENT ELEMENT VDAC1, EPCAM, LAGE3 ALOX5 3645/4885PRKDC 3043/4885GRM5 3605/4885
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL ALOX5 855/4885PRKDC 3081/4885GRM5 2093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.