Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.65 |
| ▸ | RAB9A | P51151 | 14/20 | 0.65 |
| ▸ | NPC1 | O15118 | 14/20 | 0.65 |
| ▸ | GAA | P10253 | 12/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.65 |
| ▸ | MEN1 | O00255 | 10/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.65 |
| ▸ | RELA | Q04206 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231354 | 0.90 | MAPT (0.70) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL1231353 | 0.90 | MAPT (0.70) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL1165591 | 0.84 | MAPT (0.68) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL1165592 | 0.84 | MAPT (0.68) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL28684828 | 0.81 | MAPT (0.61) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL6711569 | 0.79 | MAPT (1.00) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL6711572 | 0.79 | MAPT (1.00) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL21010612 | 0.79 | MAPT (0.68) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL13779288 | 0.79 | MAPT (0.75) | MAPTRAB9ANPC1GAAKMT2A | |
| SCHEMBL22103769 | 0.78 | MAPT (0.64) | MAPTRAB9ANPC1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630481-B1 | A method and kit for detecting alkylating agents | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2017-09-13 | — | — | EP | disclosed |
| WO-2012052747-A2 | A METHOD AND DEVICE FOR DETECTING ALKYLATING AGENTS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2012-04-26 | — | — | WO | disclosed |