Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003967 | 1.00 | MAPT (0.40) | MAPTMAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL825301 | 0.88 | MAPT (0.49) | MAPTMAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL825302 | 0.88 | MAPT (0.49) | MAPTMAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL29883561 | 0.88 | MAPT (0.49) | MAPTMAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL10001953 | 0.87 | NSD2 (0.31) | L3MBTL1 | |
| SCHEMBL30063008 | 0.80 | MAPT (0.41) | MAPTMAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL1006020 | 0.79 | MAPT (0.49) | MAPTMAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL1006022 | 0.79 | MAPT (0.49) | MAPTMAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL12107154 | 0.78 | THRB (0.41) | MAPTMAPK1L3MBTL1RAB9ANPC1 | |
| SCHEMBL2589702 | 0.78 | THRB (0.41) | MAPTMAPK1L3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564245-B1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | ALCON INC (CH) | 2021-01-27 | — | — | EP | claimed |
| EP-2451875-B1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2013-08-28 | — | — | EP | claimed |
| EP-2564245-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | Novartis AG (CH) | 2013-03-06 | — | — | EP | claimed |
| US-8262948-B2 | Intraocular lenses with combinations of UV absorbers and blue light chromophores | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | claimed |
| US-8207244-B2 | Visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-06-26 | — | — | US | claimed |
| EP-2451875-A2 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | Novartis AG (CH) | 2012-05-16 | — | — | EP | claimed |
| WO-2011137142-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | NOVARTIS AG (CH) | 2011-11-03 | — | — | WO | claimed |
| WO-2011005713-A2 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-01-13 | — | — | WO | claimed |
| US-20110003910-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-01-06 | — | — | US | claimed |
| EP-2564245-B1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | ALCON INC (CH) | 2021-01-27 | — | — | EP | disclosed |
| EP-2451875-B1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2013-08-28 | — | — | EP | disclosed |
| EP-2564245-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | Novartis AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| US-8262948-B2 | Intraocular lenses with combinations of UV absorbers and blue light chromophores | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | disclosed |
| US-8207244-B2 | Visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-06-26 | — | — | US | disclosed |
| EP-2451875-A2 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | Novartis AG (CH) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011137142-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | NOVARTIS AG (CH) | 2011-11-03 | — | — | WO | disclosed |
| US-20110266505-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | ALCON INC. (CH) | 2011-11-03 | — | — | US | disclosed |
| WO-2011005713-A2 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-01-13 | — | — | WO | disclosed |
| US-20110003910-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003910-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | CRY1, CRY2, CRYAA | MAPT 557/4885MAPK1 4517/4885L3MBTL1 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.