Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157597 | 0.88 | CYP3A4 (0.37) | ALOX5EGFRPTGS2LPAR3 | |
| SCHEMBL191427 | 0.88 | EGFR (0.38) | ALOX5EGFRPTGS2HMGCRTYR | |
| SCHEMBL13013083 | 0.88 | ALOX5 (0.41) | ALOX5EGFRPTGS2ENPP2CETP | |
| SCHEMBL28177157 | 0.85 | HMGCR (0.38) | ALOX5EGFRPTGS2HMGCRENPP2 | |
| SCHEMBL9818278 | 0.84 | TYR (0.36) | ALOX5EGFRPTGS2HMGCRENPP2 | |
| SCHEMBL9502006 | 0.84 | ENPP2 (0.51) | ALOX5EGFRPTGS2ENPP2TYR | |
| SCHEMBL5094522 | 0.82 | CETP (0.42) | ALOX5EGFRPTGS2CETPTYR | |
| SCHEMBL17865610 | 0.81 | ALOX5 (0.40) | ALOX5EGFRPTGS2HMGCRCETP | |
| SCHEMBL10982120 | 0.80 | ALOX5 (0.42) | ALOX5EGFRPTGS2ENPP2TYR | |
| SCHEMBL28050116 | 0.80 | S1PR1 (0.42) | ALOX5EGFRPTGS2CETPTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143324-B2 | antioxidants with hindered phenol functionality perform better in curing of polybenzocyclobutene materials in air without undue degradation of key properties | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-03-27 | — | — | US | disclosed |
| US-8062816-B2 | Phosphonate hole blocking layer photoconductors | XEROX CORPORATION (US) | 2011-11-22 | — | — | US | disclosed |
| EP-2042547-B1 | Benzocyclobutene based polymer formulations | DOW GLOBAL TECHNOLOGIES INC (US) | 2010-12-22 | — | — | EP | disclosed |
| EP-1802693-B1 | BENZOCYCLOBUTENE BASED POLYMER FORMULATIONS AND METHODS FOR PROCESSING SUCH FORMULATIONS IN OXIDATIVE ENVIRONMENTS | DOW GLOBAL TECHNOLOGIES INC (US) | 2010-08-04 | — | — | EP | disclosed |
| US-20090297967-A1 | PHOSPHONATE HOLE BLOCKING LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090275673-A1 | Benzocyclobutene based polymer formulations and methods for processing such formulations in oxidative environments | DOW GLOBAL TECHNOLOGIES LLC | 2009-11-05 | — | — | US | disclosed |
| EP-2042547-A1 | Benzocyclobutene based polymer formulations | Dow Global Technologies Inc. (US) | 2009-04-01 | — | — | EP | disclosed |
| US-7479507-B2 | Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs | HELLER ADAM | 2009-01-20 | — | — | US | disclosed |