Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039964 | 0.88 | ALOX5 (0.38) | LPAR3ALOX5EGFRPTGS2 | |
| SCHEMBL13013083 | 0.85 | ALOX5 (0.41) | ALOX5EGFRPTGS2 | |
| SCHEMBL6045059 | 0.83 | CYP3A4 (0.48) | CYP3A4LPAR3LPAR1LPAR2 | |
| SCHEMBL4816988 | 0.82 | LPAR3 (0.42) | LPAR3LPAR1LPAR2ALOX5PTGS2 | |
| SCHEMBL9502006 | 0.82 | ENPP2 (0.51) | CYP3A4ALOX5EGFRPTGS2 | |
| SCHEMBL5094522 | 0.79 | CETP (0.42) | CYP3A4ALOX5EGFRPTGS2 | |
| SCHEMBL191427 | 0.79 | EGFR (0.38) | ALOX5EGFRPTGS2 | |
| SCHEMBL7676495 | 0.79 | HMGCR (0.49) | CYP3A4 | |
| SCHEMBL10985358 | 0.78 | CYP3A4 (0.40) | CYP3A4LPAR3LPAR1LPAR2 | |
| SCHEMBL10982120 | 0.78 | ALOX5 (0.42) | ALOX5EGFRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630424-B2 | Roll shaped thermosensitive recording material with improved inter-plates accuracy by imparting the variation (R) of thickness in the lateral direction of not greater than 3 micrometers | RICOH COMPANY, LTD. (JP) | 2003-10-07 | — | — | US | disclosed |
| EP-1010542-B1 | Thermosensitive recording material | RICOH KK (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-20010018403-A1 | Thermosensitive recording material, block copy sheet using the recording material and printing plate prepared by using the block copy sheet | RICOH COMPANY, LTD. | 2001-08-30 | — | — | US | disclosed |
| EP-1010542-A1 | Thermosensitive recording material | Ricoh Company, Ltd. (JP) | 2000-06-21 | — | — | EP | disclosed |