Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28050116 | 0.89 | S1PR1 (0.42) | CETPALOX5PTGS2TYREGFR | |
| SCHEMBL3826368 | 0.85 | ALOX5 (0.48) | CETPALOX5PTGS2TYRS1PR1 | |
| SCHEMBL15809436 | 0.84 | TSHR (0.42) | CETPALOX5PTGS2TYREGFR | |
| SCHEMBL17510123 | 0.84 | ALOX5 (0.38) | CETPALOX5PTGS2TYREGFR | |
| SCHEMBL17865610 | 0.84 | ALOX5 (0.40) | CETPALOX5PTGS2TYREGFR | |
| SCHEMBL10039964 | 0.82 | ALOX5 (0.38) | CETPALOX5PTGS2TYREGFR | |
| SCHEMBL7157597 | 0.79 | CYP3A4 (0.37) | ALOX5PTGS2EGFRCYP3A4 | |
| SCHEMBL13013083 | 0.79 | ALOX5 (0.41) | CETPALOX5PTGS2TYREGFR | |
| SCHEMBL2706219 | 0.79 | ALOX5 (0.49) | ALOX5PTGS2TYREGFRMAOA | |
| SCHEMBL9502006 | 0.78 | ENPP2 (0.51) | ALOX5PTGS2TYREGFRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040482-A1 | POLYOLEFIN COMPOSITION WITH INCREASED RESISTANCE TO CIO2-CONTAINING WATER | BOREALIS TECHNOLOGY OY (FI) | 2008-04-10 | — | — | WO | disclosed |