SCHEMBL10040972

SCHEMBL10040972

Oc1c(/C=N/[C@@H]2CCCC[C@H]2NCc2cc3ccccc3c(-c3c(-c4ccccc4)ccc4ccccc34)c2O)cc2ccccc2c1-c1c(-c2ccccc2)ccc2ccccc12

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MPI P34949 1/20 0.31
SSTR3 P32745 1/20 0.31
CD274 Q9NZQ7 2/20 0.30
PDCD1 Q15116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10300813 1.00 L3MBTL1 (0.33) L3MBTL1ALDH1A1MAPTMPISSTR3
SCHEMBL10300871 1.00 L3MBTL1 (0.33) L3MBTL1ALDH1A1MAPTMPISSTR3
SCHEMBL10300809 1.00 L3MBTL1 (0.33) L3MBTL1ALDH1A1MAPTMPISSTR3
SCHEMBL10040974 1.00 L3MBTL1 (0.33) L3MBTL1ALDH1A1MAPTMPISSTR3
SCHEMBL14765562 0.89 ANPEP (0.31) ALDH1A1MAPTMPI
SCHEMBL13929516 0.89 ANPEP (0.31) ALDH1A1MAPTMPI
SCHEMBL13951685 0.89 ANPEP (0.31) ALDH1A1MAPTMPI
SCHEMBL10040968 0.86 L3MBTL1 (0.44) L3MBTL1ALDH1A1MAPTMPI
SCHEMBL10040967 0.86 L3MBTL1 (0.44) L3MBTL1ALDH1A1MAPTMPI
SCHEMBL14765555 0.85 MAPT (0.37) L3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8410295-B2 Method for production of optically active epoxy compound, and complex used therefor and process for producing the same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2013-04-02 US disclosed
US-8410295-B2 Method for production of optically active epoxy compound, and complex used therefor and process for producing the same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2013-04-02 US disclosed
US-8394974-B2 Process for producing optically active chromene oxide compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-03-12 US disclosed
US-20120178954-A1 METHOD FOR PRODUCTION OF OPTICALLY ACTIVE EPOXY COMPOUND, AND COMPLEX USED THEREFOR AND PROCESS FOR PRODUCING THE SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-07-12 US disclosed
US-20120178954-A1 METHOD FOR PRODUCTION OF OPTICALLY ACTIVE EPOXY COMPOUND, AND COMPLEX USED THEREFOR AND PROCESS FOR PRODUCING THE SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-07-12 US disclosed
US-8163941-B2 Reacting an unsaturated compound with oxidier in presence of a oxidation catalyst JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-04-24 US disclosed
US-8163941-B2 Reacting an unsaturated compound with oxidier in presence of a oxidation catalyst JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-04-24 US disclosed
US-20080071099-A1 Method for Production of Optically Active Epoxy Compound, and Complex Used Therefor and Process for Producing the Same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-03-20 US disclosed
US-20080071099-A1 Method for Production of Optically Active Epoxy Compound, and Complex Used Therefor and Process for Producing the Same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080071099-A1 Method for Production of Optically Active Epoxy Compound, and Complex Used Therefor and Process for Producing the Same EPRS1, PPOX, POR L3MBTL1 3054/4885ALDH1A1 840/4885MAPT 4881/4885
US-20120178954-A1 METHOD FOR PRODUCTION OF OPTICALLY ACTIVE EPOXY COMPOUND, AND COMPLEX USED THEREFOR AND PROCESS FOR PRODUCING THE SAME CYP4F11, CYP51A1, COASY L3MBTL1 3098/4885ALDH1A1 2091/4885MAPT 4823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.