Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041428 | 1.00 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL10041427 | 1.00 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL10041424 | 1.00 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL4373923 | 0.84 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL6549892 | 0.84 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL6550392 | 0.84 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL12332692 | 0.75 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL10071256 | 0.75 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL12332934 | 0.75 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL10071257 | 0.75 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664206-B2 | Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-20120165300-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-06-28 | — | — | US | disclosed |
| US-20110237557-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165300-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | CYP24A1, CYP2R1, CYP27B1 | ALDH1A1 759/4885 |
| US-20110237557-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | CYP24A1, CYP2R1, CYP27B1 | ALDH1A1 759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.