Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12332934 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL10071256 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL12332692 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL14303886 | 0.81 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL6549892 | 0.79 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL6550392 | 0.79 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL4373923 | 0.79 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL21925343 | 0.79 | RIPK1 (0.37) | TSHR | |
| SCHEMBL5370214 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHR | |
| SCHEMBL10041429 | 0.75 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165300-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165300-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | CYP24A1, CYP2R1, CYP27B1 | ALDH1A1 759/4885TSHR 2294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.