SCHEMBL10041563

SCHEMBL10041563

Ic1ccc2c(c1)c1cc(-c3ccc4c(c3)c3cc(I)ccc3n4-c3ccccc3)ccc1n2-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.48
KDM4E B2RXH2 4/20 0.48
ATM Q13315 1/20 0.48
DNMT1 P26358 1/20 0.37
JAK2 O60674 1/20 0.35
JAK3 P52333 1/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
LMNA P02545 2/20 0.34
IL1R1 P14778 1/20 0.34
HPGD P15428 3/20 0.34
HTT P42858 3/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 2/20 0.34
HSD17B10 Q99714 2/20 0.34
TSHR P16473 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3382322 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMDNMT1JAK2
SCHEMBL17658828 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMDNMT1JAK2
SCHEMBL29589862 0.93 KDM4E (0.56) L3MBTL1KDM4EATMDNMT1JAK2
SCHEMBL45663 0.93 KDM4E (0.56) L3MBTL1KDM4EATMDNMT1JAK2
SCHEMBL18435649 0.88 L3MBTL1 (0.58) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL530659 0.88 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL18823514 0.88 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL21913958 0.88 GAA (0.40) L3MBTL1KDM4EATMGAAKMT2A
SCHEMBL29287489 0.88 L3MBTL1 (0.42) L3MBTL1KDM4EATMJAK2KMT2A
SCHEMBL296550 0.87 L3MBTL1 (0.67) L3MBTL1KDM4EATMDNMT1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2603541-B1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2021-04-21 EP disclosed
EP-2603540-B1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2021-04-21 EP disclosed
EP-2732479-B1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-11 EP disclosed
US-9583717-B2 Compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
US-9583717-B2 Compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
US-9102797-B2 Polymers with carbazole structural units MERCK PATENT GMBH (DE) 2015-08-11 US disclosed
US-9102797-B2 Polymers with carbazole structural units MERCK PATENT GMBH (DE) 2015-08-11 US disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 US disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 US disclosed
US-20140138661-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-22 US disclosed
US-20140138661-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-22 US disclosed
US-20130150527-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-13 US disclosed
US-20130150527-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-13 US disclosed
US-20130137818-A1 POLYMERS HAVING CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2013-05-30 US disclosed
US-20130137818-A1 POLYMERS HAVING CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2013-05-30 US disclosed
WO-2012019724-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2012-02-16 WO disclosed
WO-2012019725-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2012-02-16 WO disclosed