SCHEMBL45663

SCHEMBL45663

Ic1ccc2c(c1)c1cc(I)ccc1n2-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
ATM Q13315 1/20 0.56
DNMT1 P26358 1/20 0.40
JAK2 O60674 1/20 0.39
JAK3 P52333 1/20 0.39
GAA P10253 2/20 0.38
GFER P55789 1/20 0.38
KMT2A Q03164 3/20 0.38
MAPK1 P28482 2/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 2/20 0.38
HPGD P15428 3/20 0.37
HSD17B10 Q99714 2/20 0.37
HTT P42858 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589862 1.00 KDM4E (0.56) KDM4EL3MBTL1ATMDNMT1JAK2
SCHEMBL13706013 0.94 KDM4E (0.50) KDM4EL3MBTL1ATMDNMT1JAK2
SCHEMBL296550 0.94 L3MBTL1 (0.67) KDM4EL3MBTL1ATMDNMT1JAK2
SCHEMBL27883966 0.94 L3MBTL1 (0.67) KDM4EL3MBTL1ATMDNMT1JAK2
SCHEMBL10041563 0.93 L3MBTL1 (0.48) KDM4EL3MBTL1ATMDNMT1JAK2
SCHEMBL12196246 0.91 L3MBTL1 (0.62) KDM4EL3MBTL1ATMDNMT1JAK2
SCHEMBL17750894 0.89 KDM4E (0.46) KDM4EL3MBTL1ATMDNMT1GAA
SCHEMBL3382322 0.89 L3MBTL1 (0.46) KDM4EL3MBTL1ATMDNMT1JAK2
SCHEMBL19695654 0.89 L3MBTL1 (0.46) KDM4EL3MBTL1ATMDNMT1JAK2
SCHEMBL15158455 0.89 L3MBTL1 (0.46) KDM4EL3MBTL1ATMDNMT1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2026-01-27 US disclosed
CN-108117543-B Novel compound and organic electroluminescent device comprising the same 东进世美肯株式会社 2023-09-12 CN disclosed
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-30 US disclosed
US-20230090208-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications UDC IRELAND LTD (IE) 2023-03-23 US disclosed
US-11450812-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2022-09-20 US disclosed
CN-114315840-A 4H-imidazo [1,2-a ] imidazoles for electronic applications UDC 爱尔兰有限责任公司 2022-04-12 CN disclosed
EP-3640252-B1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2022-03-16 EP disclosed
CN-113880763-A Organic compound, and electronic element and electronic device using same 陕西莱特光电材料股份有限公司 2022-01-04 CN disclosed
CN-106188065-B 4H-imidazo [1,2-a ] imidazoles for electronic applications UDC 爱尔兰有限责任公司 2021-12-28 CN disclosed
US-10658693-B2 Flow battery PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2020-05-19 US disclosed
US-20070037011-A1 Arylamine compound and synthetic method thereof SEMICONDUCTOR ENERGY LABORATORY CO. (JP) 2007-02-15 US disclosed
US-20070037011-A1 Arylamine compound and synthetic method thereof SEMICONDUCTOR ENERGY LABORATORY CO. (JP) 2007-02-15 US disclosed
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 US disclosed
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 US disclosed
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 US disclosed
WO-2007015407-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL OBTAINED BY USING CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-02-08 WO disclosed
WO-2006070912-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING THE CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-07-06 WO disclosed
WO-2006059745-A1 LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-06-08 WO disclosed
WO-2006043647-A1 CARBAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-04-27 WO disclosed
US-20050031899-A1 Carbazole derivative, organic semiconductor element, light emitting element, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2005-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11450812-B2 4H-imidazo[1,2-a]imidazoles for electronic applications PAH, NISCH, KCNH1 KDM4E 1128/4885L3MBTL1 4627/4885ATM 3506/4885
US-20050031899-A1 Carbazole derivative, organic semiconductor element, light emitting element, and electronic device GNA11, GNAO1, NOD1 KDM4E 4195/4885L3MBTL1 475/4885ATM 1875/4885
US-20230096132-A1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND LAGE3, ELOC, ELOB KDM4E 1841/4885L3MBTL1 280/4885ATM 3575/4885
US-12538704-B2 4H-imidazo[1,2-a]imidazoles for electronic applications RIF1, NR2E1, NR3C1 KDM4E 2068/4885L3MBTL1 2761/4885ATM 3246/4885
US-20230090208-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications PAH, NISCH, KCNH1 KDM4E 1128/4885L3MBTL1 4627/4885ATM 3506/4885
US-20070037011-A1 Arylamine compound and synthetic method thereof AHR, CYP2A13, ARNT KDM4E 1083/4885L3MBTL1 3507/4885ATM 1463/4885
US-10658693-B2 Flow battery SCO2, GZMB, JAK1 KDM4E 4103/4885L3MBTL1 2482/4885ATM 2355/4885
US-20070031701-A1 Carbazole derivative, light-emitting element material obtained by using carbazole derivative, light-emitting element, and electronic device CYP1A1, GRIA1, GNA11 KDM4E 2231/4885L3MBTL1 221/4885ATM 1256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.