SCHEMBL1004249

SCHEMBL1004249

C=CC(C)(C)OP(=O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.33
LMNA P02545 1/20 0.33
FDPS P14324 2/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LPAR2 Q9HBW0 1/20 0.30
LPAR3 Q9UBY5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11336328 0.84 LMNA (0.33) LMNAFDPS
SCHEMBL21571158 0.82 BTN3A1 (0.37)
SCHEMBL15752030 0.82 SMPD1 (0.32) SMPD1LMNAFDPSBLMTDP1
SCHEMBL156446 0.81 BTN3A1 (0.38) FDPSBLMTDP1
SCHEMBL9901912 0.80 LMNA (0.31) LMNA
Pyrophosphoric Acid SCHEMBL5062989 0.80 FDPS (0.42) FDPSBLMTDP1
Pyrophosphoric Acid SCHEMBL3890468 0.80 FDPS (0.42) FDPSBLMTDP1
Ammonia Solution, Strong SCHEMBL3690678 0.80 BTN3A1 (0.37) FDPSBLMTDP1
Ammonia Solution, Strong SCHEMBL3690680 0.80 BTN3A1 (0.37) FDPSBLMTDP1
SCHEMBL18486678 0.78 BTN3A1 (0.36) FDPSBLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12480144-B2 Cannabinoid synthase variants and methods for their use CREO INGREDIENTS, INC. (US) 2025-11-25 US claimed
US-12084704-B2 Methods for producing isobutene from 3-methylcrotonic acid GLOBAL BIOENERGIES (FR) 2024-09-10 US claimed
CN-117867044-B Biological enzyme method preparation technology of vitamin MK-4 杭州微远生物科技有限公司 2024-07-30 CN claimed
EP-4392564-A1 MICROBIAL FERMENTATION FOR THE PRODUCTION OF ISOPRENOID ALCOHOLS AND DERIVATIVES Lanzatech, Inc. (US) 2024-07-03 EP claimed
CN-110914441-B Improved process for producing isobutene from 3-methylcrotonic acid 环球生物能源公司 2024-06-28 CN claimed
CN-117836419-A Method for transducing immune cells 朗泽科技有限公司 2024-04-05 CN claimed
EP-3622080-B1 IMPROVED METHODS FOR PRODUCING ISOBUTENE FROM 3-METHYLCROTONIC ACID GLOBAL BIOENERGIES (FR) 2024-03-27 EP claimed
US-20230383321-A1 IMPROVED METHOD FOR THE PRODUCTION OF ISOPRENOIDS BASF SE (DE) 2023-11-30 US claimed
US-20230167468-A1 CANNABINOID SYNTHASE VARIANTS AND METHODS FOR THEIR USE CREO INGREDIENTS, INC. 2023-06-01 US claimed
US-20230090600-A1 MICROBIAL FERMENTATION FOR THE PRODUCTION OF ISOPRENOID ALCOHOLS AND DERIVATIVES LANZATECH, INC. 2023-03-23 US claimed
US-20120202234-A1 METHODS AND COMPOSITION FOR ISOPRENOID DIPHOSPHATE SYNTHESIS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2012-08-09 US claimed
US-8153426-B2 selecting from human peripheral blood mononuclear cells, treating the selected cells with a stimulus isopentenyl pyrophosphate, induce strong primary and secondary T helper cell and cytotoxic T cell responses; biodrugs, or vaccination against tumor, infectious diseases UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2012-04-10 US claimed
WO-2011009132-A2 METHODS AND COMPOSITION FOR ISOPRENOID DIPHOSPHATE SYNTHESIS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2011-01-20 WO claimed
US-20090130074-A1 PREPARATION OF ANTIGEN-PRESENTING HUMAN GAMMA DELTA T CELLS AND USE IN IMMUNOTHERAPY UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2009-05-21 US claimed
EP-1088333-A4 COMPOSITIONS AND METHODS FOR INHIBITING BONE RESORPTION MERCK & CO INC (US) 2005-08-10 EP claimed
US-6699850-B2 ORAL FORMULATION OF A COMBINATION OF NITROGEN-CONTAINING BISPHOSPHONATE OR ITS SALT AND AN ISOPRENOID COMPOUND FOR INHIBITING BONE RESOPRTION IN A MAMMAL WHILE COUNTERACTING THE OCCURRENCE OF ADVERSE GASTROINTESTINAL EFFECT MERCK & CO., INC. 2004-03-02 US claimed
US-20020082244-A1 Compositions and methods for inhibiting bone resorption MERCK & CO., INC. 2002-06-27 US claimed
EP-1088333-A1 COMPOSITIONS AND METHODS FOR INHIBITING BONE RESORPTION Merck & Co., Inc. (US) 2001-04-04 EP claimed
WO-1999067809-A9 COMPOSITIONS AND METHODS FOR INHIBITING BONE RESORPTION MERCK & CO INC (US) 2001-03-22 WO claimed
WO-1999067809-A1 COMPOSITIONS AND METHODS FOR INHIBITING BONE RESORPTION MERCK & CO., INC. (US) 1999-12-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020082244-A1 Compositions and methods for inhibiting bone resorption SOST, PTEN, ALPI SMPD1 271/4885LMNA 3178/4885FDPS 498/4885
US-20090130074-A1 PREPARATION OF ANTIGEN-PRESENTING HUMAN GAMMA DELTA T CELLS AND USE IN IMMUNOTHERAPY CD4, IFNG, CD74 SMPD1 1195/4885LMNA 4630/4885FDPS 2888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.